Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats.
about
Genetics in non-genetic model systemsMTH1 inhibition eradicates cancer by preventing sanitation of the dNTP poolThe chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiationARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune systemSynthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive functionInducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown.Generation and characterization of a Tet-On (rtTA-M2) transgenic ratInducible gene expression in tumors colonized by modified oncolytic vaccinia virus strainsLentiviral-mediated transgene expression can potentiate intestinal mesenchymal-epithelial signaling.Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance.Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expressionInducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression.Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.Doxycycline Inducible Melanogenic Vaccinia Virus as Theranostic Anti-Cancer Agent.Progress on RNAi-based molecular medicines.Targeting Mdmx to treat breast cancers with wild-type p53.MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage responsePTPN22 silencing in the NOD model indicates the type 1 diabetes-associated allele is not a loss-of-function variant.SERPINB1 expression is predictive for sensitivity and outcome of cisplatin-based chemotherapy in melanoma.E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis.ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.Lentiviral delivery of short hairpin RNAsTargeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.MDM4 is a rational target for treating breast cancers with mutant p53.Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP.An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells.Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.Genome-wide binding of transcription factors in inv(16) acute myeloid leukemia.CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.Knockdown of AMP-activated protein kinase alpha 1 and alpha 2 catalytic subunits.Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cellsE6AP promotes prostate cancer by reducing p27 expressionHepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM.Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector.Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo.Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.CD52 inhibits Toll-like receptor activation of NF-κB and triggers apoptosis to suppress inflammation.Stable silencing of the glucocorticoid receptor in myelin-specific T effector cells by retroviral delivery of shRNA: insight into neuroinflammatory disease.
P2860
Q26852316-444D19AA-F46A-47BD-8A1E-3BA9CDCF0D80Q27643976-E0499FC1-6DC5-458F-BE25-A633CEBA80D2Q28511329-A5F8541E-AA86-4B48-A505-EEC806691613Q28593507-6F0E181C-F029-43A9-A187-B0519AA875D5Q30448321-E2B914B1-1D0E-4CC6-AE22-FEBD20F5EE5DQ33425855-C8039D5C-33CA-4360-A7D1-BEA748BAAF44Q33531551-2D41208D-70AA-4099-BC70-A471AA8909D7Q34262005-B4667B25-2F6B-4443-A709-7B5BD676E9B8Q34663671-0EF28958-C6AD-499F-B4FB-521AF5243AEEQ35142784-B71A798D-3388-4825-BEBE-B4F92D450567Q35237727-B5467B4F-D5E5-4161-8A6B-126B9A3A3924Q35576955-9E32C675-E460-4A86-AB86-A69737818A61Q35852248-DE568B81-E85D-467A-B08A-4F2FEC88B283Q35868856-57AAE6A2-A6BB-4C6E-B1DA-20C5F654438AQ36161380-05A4BDDB-880E-434A-A1D6-4563158BD91BQ36293839-A29E0222-5A85-43AD-AF03-269E0F4F761AQ36474852-2BE393F4-4DDB-4E54-83B8-ABCBB5CAD1F0Q36635245-86DE996D-770C-43D9-B9AC-38ABA0A654EEQ36962895-5DBFFCD8-A721-4E50-A939-2774D6DF8F2BQ37006778-61AA7DAA-A202-46F9-81D8-705CC381D2E7Q37023688-36D6CA4A-B335-4D7C-847E-27D9D6843D95Q37430557-B2D41FB0-ABE2-4AEC-A174-6580A2FD9F83Q37488736-4436FDA5-95C3-4C8A-9BB8-1BDAF4248E21Q37686014-D40A9ABD-C16A-4A0B-A685-409590F137F6Q38720844-C6A89111-CB16-4AF5-BFD5-40B9734FAF4FQ38745588-1C9667EA-39A4-4ED6-8A0E-6912B7ED52F1Q39574886-40E46A79-B895-4F70-861E-173D2D046810Q40267794-2A7DC6EE-9185-4594-B7F7-032708216823Q40412447-A539B695-4043-4D98-9B87-84D4488A9E99Q41073866-7C7CFAD1-2934-4D06-8D97-6FF3ED4BF763Q41908741-364E31DB-AC90-4DBC-8F52-5FC3EB2C7B11Q41928227-5776AF0C-5332-4CAC-834F-8585C54540F4Q42019839-EFFBDE83-A9C4-4C15-92B0-3089CF0B9A2EQ42335715-0EF41263-0B77-48F4-8C58-5EA36464E6F2Q42693009-9063F026-91E0-4603-88DA-A24379EF29CCQ44159687-95714969-40D0-428B-A6E7-92A25977AE66Q45888148-4BA264E2-DF37-483A-A254-F66F3B7CFD62Q46194866-698E7CFA-4B99-4286-89D8-A1D28B901EB7Q47290604-B009E4DA-68D5-4DA4-BBD3-FFA483238E4FQ48486600-97E25DF7-77F3-4778-8013-66E1B20498E3
P2860
Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Inducible and reversible gene ...... lentivirus in transgenic rats.
@en
type
label
Inducible and reversible gene ...... lentivirus in transgenic rats.
@en
prefLabel
Inducible and reversible gene ...... lentivirus in transgenic rats.
@en
P2093
P2860
P356
P1476
Inducible and reversible gene ...... lentivirus in transgenic rats.
@en
P2093
Holger M Reichardt
Jens van den Brandt
Jost Seibler
Marco J Herold
P2860
P304
18507-18512
P356
10.1073/PNAS.0806213105
P407
P577
2008-11-18T00:00:00Z