Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
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The status of Nrf2-based therapeutics: current perspectives and future prospectsMitochondria and Reactive Oxygen Species Contribute to Neurogenic Hypertension.Anti-Psoriatic Drug Monomethylfumarate Increases Nuclear Factor Erythroid 2-Related Factor 2 Levels and Induces Aquaporin-3 mRNA and Protein Expression.Epigenetic Treatment of Persistent Viral Infections.The Role of Astrocyte Dysfunction in Parkinson's Disease Pathogenesis.Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?The MPTP Story.The Role of the Nrf2/ARE Antioxidant System in Preventing Cardiovascular Diseases.Simvastatin as a Potential Disease-Modifying Therapy for Patients with Parkinson's Disease: Rationale for Clinical Trial, and Current Progress.MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model.Chlorogenic acid protects against aluminium-induced cytotoxicity through chelation and antioxidant actions in primary hippocampal neuronal cells.Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease.Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors.Dimethyl fumarate treatment after traumatic brain injury prevents depletion of antioxidative brain glutathione and confers neuroprotection.Current perspective of mitochondrial biology in Parkinson's disease.β-Guanidinopropionic Acid Stimulates Brain Mitochondria Biogenesis and Alters Cognitive Behavior in Nondiseased Mid-Age Mice.Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.p62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases
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P2860
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Distinct Nrf2 Signaling Mechan ...... ntal Parkinson's-Like Disease.
@en
type
label
Distinct Nrf2 Signaling Mechan ...... ntal Parkinson's-Like Disease.
@en
prefLabel
Distinct Nrf2 Signaling Mechan ...... ntal Parkinson's-Like Disease.
@en
P2093
P2860
P50
P1476
Distinct Nrf2 Signaling Mechan ...... ntal Parkinson's-Like Disease.
@en
P2093
Arsen Gaisin
Bobby Thomas
Dmitry M Hushpulian
Ismail Kaddour-Djebbar
John C Morgan
Lichuan Yang
M Flint Beal
Natalya Smirnova
Noel Calingasan
Wendy B Bollag
P2860
P304
P356
10.1523/JNEUROSCI.0426-16.2016
P407
P577
2016-06-01T00:00:00Z