Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system.
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Myelin management by the 18.5-kDa and 21.5-kDa classic myelin basic protein isoformsPeptidylarginine deiminases in citrullination, gene regulation, health and pathogenesisProtein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with DysregulationPeptidylarginine deiminase and protein citrullination in prion diseases: strong evidence of neurodegenerationPotential role for PAD2 in gene regulation in breast cancer cells.Proline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5-kDa myelin basic protein decrease its affinity for the Fyn-SH3 domain and alter process development and protein localization in oligodendrocytesIdentification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones.Multiple sclerosis autoantigen myelin basic protein escapes control by ubiquitination during proteasomal degradationIdentification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment methodMass spectrometric identification of citrullination sites and immunohistochemical detection of citrullinated glial fibrillary acidic protein in Alzheimer's disease brains.Chemical biology of protein arginine modifications in epigenetic regulationAdhesion and hemifusion of cytoplasmic myelin lipid membranes are highly dependent on the lipid composition.Protein Citrullination: A Proposed Mechanism for Pathology in Traumatic Brain Injury.Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis.Detection and identification of protein citrullination in complex biological systemsInhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoformsProtein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potentialModulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway.Fuzzy complexes of myelin basic protein: NMR spectroscopic investigations of a polymorphic organizational linker of the central nervous system.Epigenetics of multiple sclerosis: an updated review.Unconventional post-translational modifications in immunological signaling.Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanismA novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming.PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis.Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription.Myelin Basic Protein Citrullination in Multiple Sclerosis: A Potential Therapeutic Target for the Pathology.PAD2 Activity Monitored via a Fluorescent Substrate Analog.Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?Increased expression of PAD2 after repeated intracerebroventricular infusions of soluble Abeta(25-35) in the Alzheimer's disease model rat brain: effect of memantine.Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.And Yet it is Modified-Holding a Candle to the Dark Matter of White Matter.Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood.Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development
P2860
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P2860
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Peptidylarginine deiminase 2 ( ...... in the central nervous system.
@en
type
label
Peptidylarginine deiminase 2 ( ...... in the central nervous system.
@en
prefLabel
Peptidylarginine deiminase 2 ( ...... in the central nervous system.
@en
P2093
P2860
P356
P1476
Peptidylarginine deiminase 2 ( ...... in the central nervous system.
@en
P2093
Abdiwahab A Musse
Cameron A Ackerley
Dorothee Bienzle
Fabrizio G Mastronardi
Helena Lei
Mario A Moscarello
Roberto Poma
P2860
P304
P356
10.1242/DMM.000729
P577
2008-11-06T00:00:00Z