The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing.
about
Yersinia virulence factors - a sophisticated arsenal for combating host defencesYersinia type III effectors perturb host innate immune responsesBacteria-host relationship: ubiquitin ligases as weapons of invasionBacterial immune evasion through manipulation of host inhibitory immune signalingPyroptotic cell death defends against intracellular pathogensStructure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin LigaseModulation of the Inflammasome Signaling Pathway by Enteropathogenic and Enterohemorrhagic Escherichia coliEvasion of inflammasome activation by microbial pathogensModulation of the host innate immune and inflammatory response by translocated bacterial proteinsActivation and assembly of the inflammasomes through conserved protein domain familiesEnteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome ActivationThe Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.The Pla protease of Yersinia pestis degrades fas ligand to manipulate host cell death and inflammationMitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome.Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signalingGlutathionylation of Yersinia pestis LcrV and Its Effects on Plague PathogenesisInflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection.Burning down the house: cellular actions during pyroptosis.IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.Integrin-mediated first signal for inflammasome activation in intestinal epithelial cellsCaspase-3 mediates the pathogenic effect of Yersinia pestis YopM in liver of C57BL/6 mice and contributes to YopM's function in spleen.Bacterial secreted effectors and caspase-3 interactionsA balanced IL-1β activity is required for host response to Citrobacter rodentium infection.Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD.Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plagueHuman caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens.Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plagueImmunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host CellsCanonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.Fis Is Essential for Yersinia pseudotuberculosis Virulence and Protects against Reactive Oxygen Species Produced by Phagocytic Cells during InfectionThe Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.Macrophage cell death upon intracellular bacterial infection.Yersinia versus host immunity: how a pathogen evades or triggers a protective responseUncovering an Important Role for YopJ in the Inhibition of Caspase-1 in Activated Macrophages and Promoting Yersinia pseudotuberculosis Virulence.Manipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence.Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation.Distribution and Evolution of Yersinia Leucine-Rich Repeat Proteins
P2860
Q26747057-50D35946-102C-446A-8EF7-F7798F383206Q26765207-FE8068A8-E103-4547-8420-C02243A03633Q26766507-4FEEE9C8-26E5-4462-B8B0-8724BE50C794Q26849421-3BD23082-4043-4C6A-83D6-93BFBD0CB7BCQ27022620-D7E13307-0A62-4713-BBF8-520BF405DA8EQ27680640-73BCE1DC-7600-42B4-AC45-C704AFFF97EDQ28079739-65BBE33C-ABA8-4ACA-95FA-21FBFC1C11B8Q28082757-595D36AA-DDBA-41CC-93AE-345036B7FE93Q28083042-5852EEA1-D474-4803-AB11-494C24D240D8Q28251619-8C44E176-B4AB-4C05-ACBD-422C2139ABABQ28547711-FA01F265-C252-44BC-AEDD-A8BCA5DD1F3BQ29248184-051F141E-D341-4ED6-9EFE-C56850A01660Q33603072-F91953F4-231E-45D1-B580-9E017A5BFD1BQ33607280-BB08B4C8-7EE1-4837-B27A-2E0C309CFBABQ33626988-492DEB73-2389-4F47-A2C8-C1CB7BE8055CQ33665643-F7DA1DE7-EBC9-4F74-9324-9D14BA0991F4Q33691879-B326A426-5C9D-41FE-A5AB-6A178A4EEF23Q34036902-F693A2A5-6FF3-410E-8D1B-923126BCE858Q34039440-C9F7A828-9988-470B-84F4-EEF031B8E265Q34165365-94DFA6EB-7E6D-429B-9A0B-E8A612405473Q34241809-246CA7EB-3BA3-4D82-B0DB-4432A35D2561Q34456067-96919655-27A0-4508-A9CD-01AA2E1AE1B6Q34639643-240F61D4-8486-490F-9F6B-DDD5F1311219Q35061095-906A3A1E-3BAF-4319-8CE0-96C231F4CB6AQ35111107-8B9453C6-5A90-40E3-9FD9-7E36739EE662Q35123268-5F01F8BA-81B3-440E-A1BC-F914A6B726F2Q35189003-3B40BE3A-31B1-44E0-A9D6-2BBF0914501EQ35669235-A97EA62F-825E-4C81-B977-076F1DE082C8Q35805383-8CF64CD2-5FA0-4378-A030-C58489F77294Q36051864-6AEFE25F-5BBA-49A0-854F-24284FE928A8Q36053123-80F4C30E-3D65-4752-ADCC-5E4BC6B79C59Q36149628-6624B15B-64C2-4C02-B428-1EABD8A14B24Q36212027-B40AFB86-5E5B-465F-8A42-B2B68AD9DFFBQ36304356-ABD7522F-7DAE-450B-828A-6E4EEE1D6EB9Q36382996-D7F5AC25-B5AD-48CE-8E4D-25C6B30D5CFAQ36586461-451B0B8A-08B0-40A0-AE93-7DBBB6D654A4Q36728011-1CEC84DA-C52C-4979-A241-8B69D60A10DFQ36876293-D8214C1B-0B13-48F0-8740-80CDA5DCCDE9Q37042305-A42F1429-D0CE-4829-ADAB-ECB57F2BAE1FQ37129905-5078B589-C469-4A7E-8F19-C79C1B131B68
P2860
The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The Yersinia virulence effecto ...... asome assembly and processing.
@en
type
label
The Yersinia virulence effecto ...... asome assembly and processing.
@en
prefLabel
The Yersinia virulence effecto ...... asome assembly and processing.
@en
P2860
P1433
P1476
The Yersinia virulence effecto ...... asome assembly and processing.
@en
P2093
Brad T Cookson
P2860
P304
P356
10.1016/J.CHOM.2012.10.020
P577
2012-12-01T00:00:00Z