Trisomy correction in Down syndrome induced pluripotent stem cells. - Wikidata - awgldk - TriplyDB

Trisomy correction in Down syndrome induced pluripotent stem cells.

Trisomy correction in Down syndrome induced pluripotent stem cells.

http://www.wikidata.org/entity/Q36995232

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Modeling Kidney Disease with iPS Cells Non-embryo-destructive Extraction of Pluripotent Embryonic Stem Cells: Implications for Regenerative Medicine and Reproductive Medicine A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome Concise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem Cells Modelling human disease with pluripotent stem cells Transgene Reactivation in Induced Pluripotent Stem Cell Derivatives and Reversion to Pluripotency of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients Toward pluripotency by reprogramming: mechanisms and application Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.HLA engineering of human pluripotent stem cells Integration-defective lentiviral vector mediates efficient gene editing through homology-directed repair in human embryonic stem cells Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives.Translating dosage compensation to trisomy 21 Genomic editing tools to model human diseases with isogenic pluripotent stem cells.Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene Modeling human neurological disorders with induced pluripotent stem cells.Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic down syndrome model accelerated neuronal ageing and neurodegeneration.Chromosome transplantation as a novel approach for correcting complex genomic disorders The presence of extra chromosomes leads to genomic instability.Receptor-interacting protein 140 overexpression promotes neuro-2a neuronal differentiation by ERK1/2 signaling.Cancer karyotypes: survival of the fittest Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells Genetic and epigenetic variations in iPSCs: potential causes and implications for application Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells.Induced pluripotent stem cells as a cellular model for studying Down Syndrome.Genomic instability in pluripotent stem cells: implications for clinical applications.The effects of polymorphisms on human gene targeting.Genetic correction using engineered nucleases for gene therapy applications.Modeling neurodevelopmental disorders using human pluripotent stem cells.Stem and progenitor cell dysfunction in human trisomies.The potential of induced pluripotent stem cells in models of neurological disorders: implications on future therapy.Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions.Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential.Generation of Integration-Free Induced Pluripotent Stem Cells from Urine-Derived Cells Isolated from Individuals with Down Syndrome.Perturbations of heart development and function in cardiomyocytes from human embryonic stem cells with trisomy 21.Silent IL2RG Gene Editing in Human Pluripotent Stem Cells.Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells.

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P2860

Trisomy correction in Down syndrome induced pluripotent stem cells.

http://www.wikidata.org/entity/Q36995232

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Trisomy correction in Down syndrome induced pluripotent stem cells.

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type

label

Trisomy correction in Down syndrome induced pluripotent stem cells.

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Trisomy correction in Down syndrome induced pluripotent stem cells.

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J.STEM.2012.08.004

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P1476

Trisomy correction in Down syndrome induced pluripotent stem cells.

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P2093

Kai-Hsin Chang

http://www.w3.org/2001/XMLSchema#string

Li B Li

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Pei-Rong Wang

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Roli K Hirata

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Thalia Papayannopoulou

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P2860

Gene targeting in stem cells from individuals with osteogenesis imperfecta

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Induced pluripotent stem cell lines derived from human somatic cells

Identification of aneuploidy-tolerating mutations

Engineering of human pluripotent stem cells by AAV-mediated gene targeting.

Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.

Risks of leukaemia and solid tumours in individuals with Down's syndrome.

Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.

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10.1016/J.STEM.2012.08.004

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David W Russell

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