Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels.
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Epac signaling is required for hippocampus-dependent memory retrieval.Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivativesBlock of cyclic nucleotide-gated channels by tetracaine derivatives: role of apolar interactions at two distinct locationsHalogen substituents on the aromatic moiety of the tetracaine scaffold improve potency of cyclic nucleotide-gated channel block.New cGMP analogues restrain proliferation and migration of melanoma cells.Development of new 1,3-diazaphenoxazine derivatives (thioG-grasp) to covalently capture 8-thioguanosine.Hydrophobic alkyl chains substituted to the 8-position of cyclic nucleotides enhance activation of CNG and HCN channels by an intricate enthalpy - entropy compensation
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Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on August 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@en
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@nl
type
label
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@en
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@nl
prefLabel
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@en
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@nl
P2860
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P1476
Novel N7- and N1-substituted c ...... lic nucleotide-gated channels.
@en
P2093
Jeffrey W Karpen
Timothy Strassmaier
P2860
P304
P356
10.1021/JM0702581
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P577
2007-08-01T00:00:00Z