Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.
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Mechanism by which metformin reduces glucose production in type 2 diabetesPotential of surgery for curing type 2 diabetes mellitusCorrection of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic ratsTissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistanceAnalysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitusNovel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetesAccelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1Insulin resistance and human disease: a short history.Therapeutic dilemmas in type II diabetes mellitus--improving and maintaining beta-cell and insulin sensitivityAmylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle.MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitusLack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitusSkeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistanceReduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in noninsulin-dependent diabetic subjects. Effects of insulin therapyStudies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. Insulin action and binding in isolated hepatocytes, insulin receptor structure, and kinase activity.Pathogenesis of impaired glucose tolerance and type II diabetes mellitus--current status.The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues.Insulin resistance associated with lower rates of weight gain in Pima IndiansIntracellular glucose oxidation and glycogen synthase activity are reduced in non-insulin-dependent (type II) diabetes independent of impaired glucose uptake.Metabolic abnormalities in children of non-insulin dependent diabetics.Prevalence of cardiometabolic risk factors and metabolic syndrome in obese Kuwaiti adolescents.In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects.Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytesEffects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus.Plasma lipids and insulin in gall stone disease: a case-control studyDecreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers.Rates of noninsulin-mediated glucose uptake are elevated in type II diabetic subjects.Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes.Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes.Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistancePostprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissuesInsulin transport across capillaries is rate limiting for insulin action in dogsInfluence of hyperglycemia on insulin's in vivo effects in type II diabetesHigh dietary magnesium intake is associated with low insulin resistance in the Newfoundland populationRelationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects.Mechanism of insulin resistance in human liver cirrhosis. Evidence of a combined receptor and postreceptor defectEffect of metformin on insulin receptor binding and glycaemic control in type II diabetes.Regulation of human insulin receptor RNA splicing in vivo.
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Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1981
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@en
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@nl
type
label
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@en
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@nl
prefLabel
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@en
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@nl
P2093
P2860
P356
P1476
Receptor and postreceptor defe ...... n-dependent diabetes mellitus.
@en
P2093
J A Scarlett
O G Kolterman
P Burstein
P2860
P304
P356
10.1172/JCI110350
P407
P577
1981-10-01T00:00:00Z