A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.
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TularemiaFrom the Outside-In: The Francisella tularensis Envelope and VirulenceImmunotherapy for tularemiaSubversion of host recognition and defense systems by Francisella sppEvidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid AHost-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.In vivo Himar1-based transposon mutagenesis of Francisella tularensis.Glutathione provides a source of cysteine essential for intracellular multiplication of Francisella tularensis.Binding and activation of host plasminogen on the surface of Francisella tularensis.Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice.Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.Francisella tularensis enters macrophages via a novel process involving pseudopod loopsRoles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis2 Strain SCHU S4.A Francisella tularensis live vaccine strain (LVS) mutant with a deletion in capB, encoding a putative capsular biosynthesis protein, is significantly more attenuated than LVS yet induces potent protective immunity in mice against F. tularensis chalTransfer of immunity against lethal murine Francisella infection by specific antibody depends on host gamma interferon and T cells.IKKβ in myeloid cells controls the host response to lethal and sublethal Francisella tularensis LVS infection.Protection afforded by heat shock protein 60 from Francisella tularensis is due to copurified lipopolysaccharide.Isolation and mutagenesis of a capsule-like complex (CLC) from Francisella tularensis, and contribution of the CLC to F. tularensis virulence in miceVirulence of Francisella spp. in chicken embryos.The subversion of the immune system by francisella tularensis.Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulenceTryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense.Phagocytic receptors dictate phagosomal escape and intracellular proliferation of Francisella tularensis.Staphylococcus saprophyticus urease: characterization and contribution to uropathogenicity in unobstructed urinary tract infection of ratsMinimal requirements for murine resistance to infection with Francisella tularensis LVS.Characterization of Francisella tularensis Schu S4 mutants identified from a transposon library screened for O-antigen and capsule deficienciesRole of the wbt locus of Francisella tularensis in lipopolysaccharide O-antigen biogenesis and pathogenicityIn vivo negative selection screen identifies genes required for Francisella virulenceA defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity.Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan.Genome-wide identification of Francisella tularensis virulence determinantsFrancisella tularensis: taxonomy, genetics, and Immunopathogenesis of a potential agent of biowarfare.Development of novel plasmid vectors and a promoter trap system in Francisella tularensis compatible with the pFLN10 based plasmids.Group B streptococcal opacity variants.Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serum.Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophagesActivities of Murine Peripheral Blood Lymphocytes Provide Immune Correlates That Predict Francisella tularensis Vaccine EfficacyInitial delay in the immune response to Francisella tularensis is followed by hypercytokinemia characteristic of severe sepsis and correlating with upregulation and release of damage-associated molecular patterns.
P2860
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P2860
A capsule-deficient mutant of Francisella tularensis LVS exhibits enhanced sensitivity to killing by serum but diminished sensitivity to killing by polymorphonuclear leukocytes.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1988
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@en
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@nl
type
label
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@en
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@nl
prefLabel
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@en
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
@nl
P2093
P2860
P1476
A capsule-deficient mutant of ...... polymorphonuclear leukocytes.
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P2093
P2860
P304
P407
P577
1988-05-01T00:00:00Z