Early preplasma cells define a tolerance checkpoint for autoreactive B cells. - Wikidata - awgldk - TriplyDB

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

http://www.wikidata.org/entity/Q37006531

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Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate The riddle of the dual expression of IgM and IgD Phenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosus Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE B cell activating factor (BAFF) and T cells cooperate to breach B cell tolerance in lupus-prone New Zealand Black (NZB) mice The role of B cells in lupus pathogenesis.Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity.Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.Mature B cells class switched to IgD are autoreactive in healthy individuals Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis.IFN-α confers resistance of systemic lupus erythematosus nephritis to therapy in NZB/W F1 mice Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity Phenotyping of P105-negative B cell subsets in patients with systemic lupus erythematosus.Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE.Macrophages prevent the differentiation of autoreactive B cells by secreting CD40 ligand and interleukin-6 Autoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophages Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice.Receptor cross-talk spatially restricts p-ERK during TLR4 stimulation of autoreactive B cells.Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course Maintenance of autoantibody production in pristane-induced murine lupus.B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice B-cell anergy: from transgenic models to naturally occurring anergic B cells?Understanding B-cell tolerance through the use of immunoglobulin transgenic models.Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10 Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus B cells and immunological tolerance.IgD attenuates the IgM-induced anergy response in transitional and mature B cells.Death receptor 6 contributes to autoimmunity in lupus-prone mice.Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells.BAFF and selection of autoreactive B cells The role of activation-induced deaminase in lupus nephritis.Aberrant B cell selection and activation in systemic lupus erythematosus.T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells.Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints.Plasmacytoid dendritic cells regulate autoreactive B cell activation via soluble factors and in a cell-to-cell contact manner.Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance.The regulation of autoreactive B cells during innate immune responses.Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens.Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation.

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Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

http://www.wikidata.org/entity/Q37006531

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2006

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@en

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@nl

type

label

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@en

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@nl

prefLabel

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@en

Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@nl

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JIMMUNOL.176.2.790

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Journal of Immunology

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Early preplasma cells define a tolerance checkpoint for autoreactive B cells.

@en

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Barbara J Vilen

http://www.w3.org/2001/XMLSchema#string

Brian P O'Conner

http://www.w3.org/2001/XMLSchema#string

Donna A Culton

http://www.w3.org/2001/XMLSchema#string

Jennifer Rutan

http://www.w3.org/2001/XMLSchema#string

Kara L Conway

http://www.w3.org/2001/XMLSchema#string

Ramiro Diz

http://www.w3.org/2001/XMLSchema#string

Stephen H Clarke

http://www.w3.org/2001/XMLSchema#string

P2860

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

Regulatory mechanisms that determine the development and function of plasma cells

BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases

BLyS and B cell autoimmunity

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

BCMA is essential for the survival of long-lived bone marrow plasma cells

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790-802

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scholarly article

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10.4049/JIMMUNOL.176.2.790

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P433

2

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176

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2006-01-01T00:00:00Z

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7377486

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16393962

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3709567

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