P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis - Wikidata - awgldk - TriplyDB

P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

http://www.wikidata.org/entity/Q37008361

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Cross talk between cardiac myocytes and fibroblasts: from multiscale investigative approaches to mechanisms and functional consequences Pregnancy protects against antiangiogenic and fibrogenic effects of angiotensin II in rat hearts Uridine triphosphate (UTP) induces profibrotic responses in cardiac fibroblasts by activation of P2Y2 receptors TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis.Regulation of cellular communication by signaling microdomains in the blood vessel wall.Array data extractor (ADE): a LabVIEW program to extract and merge gene array data.TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.Cardiac purinergic signalling in health and disease Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis Connexins, Pannexins, and Their Channels in Fibroproliferative Diseases Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y 2 agonist, on cardiomyocytes in neonatal rats.Inhibition of periostin expression protects against the development of renal inflammation and fibrosis.P2Y nucleotide receptors: promise of therapeutic applications Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow.Pannexin 1 constitutes the large conductance cation channel of cardiac myocytes Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.β-arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarction Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.Coupling of P2Y receptors to G proteins and other signaling pathways Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells Lipoapoptosis induced by saturated free fatty acids stimulates monocyte migration: a novel role for Pannexin1 in liver cells.Vesicular and conductive mechanisms of nucleotide release.ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y2 receptors.Induction of cardiac fibrosis by β-blocker in G protein-independent and G protein-coupled receptor kinase 5/β-arrestin2-dependent Signaling pathways.Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations.AMP-activated protein kinase as regulator of P2Y(6) receptor-induced insulin secretion in mouse pancreatic β-cells Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.A new perspective of mechanosensitive pannexin-1 channels in cancer metastasis: clues for the treatment of other stress-induced diseases.NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.Hydrolysis of extracellular ATP by ectonucleoside triphosphate diphosphohydrolase (ENTPD) establishes the set point for fibrotic activity of cardiac fibroblasts.Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition.Emerging role of G protein-coupled receptors in microvascular myogenic tone.Revisited and revised: is RhoA always a villain in cardiac pathophysiology?

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P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

http://www.wikidata.org/entity/Q37008361

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

P2Y6 receptor-Galpha12/13 sign ...... rload-induced cardiac fibrosis

@en

P2Y6 receptor-Galpha12/13 sign ...... load-induced cardiac fibrosis.

@nl

type

label

P2Y6 receptor-Galpha12/13 sign ...... rload-induced cardiac fibrosis

@en

P2Y6 receptor-Galpha12/13 sign ...... load-induced cardiac fibrosis.

@nl

prefLabel

P2Y6 receptor-Galpha12/13 sign ...... rload-induced cardiac fibrosis

@en

P2Y6 receptor-Galpha12/13 sign ...... load-induced cardiac fibrosis.

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The EMBO Journal

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P2Y6 receptor-Galpha12/13 sign ...... rload-induced cardiac fibrosis

@en

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Aya Uemura

http://www.w3.org/2001/XMLSchema#string

Hidetoshi Tozaki-Saitoh

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Hitoshi Kurose

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Kazuhide Inoue

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Kazuhiro Suzuki

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Michio Nakaya

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Motohiro Nishida

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Taku Nagao

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Tomomi Ide

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Yoji Sato

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P2860

Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitment

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

Regulation and functions of Rho-associated kinase

Adenosine 5'-triphosphate: a P2-purinergic agonist in the myocardium

Pannexins and gap junction protein diversity

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

G alpha(i) and G alpha(o) are target proteins of reactive oxygen species

Periostin as a novel factor responsible for ventricular dilation

Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

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3104-3115

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10.1038/EMBOJ.2008.237

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23

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27

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2008-11-13T00:00:00Z

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19008857

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