Pbx1 restrains myeloid maturation while preserving lymphoid potential in hematopoietic progenitors.
about
Prep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway.Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors.Estrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice.Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling.PBX1 as Pioneer Factor: A Case Still Open.TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.The central nervous system microenvironment influences the leukemia transcriptome and enhances leukemia chemo-resistance.Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme.Molecular processes involved in B cell acute lymphoblastic leukaemia.ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity.The PBX1 lupus susceptibility gene regulates CD44 expression.Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface.
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Pbx1 restrains myeloid maturation while preserving lymphoid potential in hematopoietic progenitors.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 May 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
@en
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
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type
label
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
@en
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
@nl
prefLabel
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
@en
Pbx1 restrains myeloid maturat ...... in hematopoietic progenitors.
@nl
P2093
P2860
P356
P1476
Pbx1 restrains myeloid maturat ...... l in hematopoietic progenitors
@en
P2093
Chenwei Lin
Kevin S Smith
Luca Zammataro
Masayuki Iwasaki
Michael L Cleary
P2860
P304
P356
10.1242/JCS.125435
P407
P577
2013-05-09T00:00:00Z