Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit
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Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferiReviewing molecular adaptations of Lyme borreliosis spirochetes in the context of reproductive fitness in natural transmission cyclesCrystal structure of Lyme disease antigen outer surface protein A complexed with an FabThe 93-kilodalton protein of Borrelia burgdorferi: an immunodominant protoplasmic cylinder antigen.110-kilodalton recombinant protein which is immunoreactive with sera from humans, dogs, and horses with Lyme borreliosis.Regulation of expression of major outer surface proteins in Borrelia burgdorferi.An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.Expression of the bmpB gene of Borrelia burgdorferi is modulated by two distinct transcription termination eventsAccess of antibody or trypsin to an integral outer membrane protein (P66) of Borrelia burgdorferi is hindered by Osp lipoproteins.Alternate sigma factor RpoS is required for the in vivo-specific repression of Borrelia burgdorferi plasmid lp54-borne ospA and lp6.6 genes.Role of attached lipid in immunogenicity of Borrelia burgdorferi OspAA monoclonal antibody to OspA inhibits association of Borrelia burgdorferi with human endothelial cells.Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice.Two regulatory elements required for enhancing ospA expression in Borrelia burgdorferi grown in vitro but repressing its expression during mammalian infection.Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi.Conservation of plasmid maintenance functions between linear and circular plasmids in Borrelia burgdorferi.Clonal polymorphisms of outer membrane protein OspB of Borrelia burgdorferi.BosR functions as a repressor of the ospAB operon in Borrelia burgdorferi.Cloning and sequencing of the gene encoding the outer surface protein A (OspA) of a European Borrelia burgdorferi isolateAnalysis of promoters in Borrelia burgdorferi by use of a transiently expressed reporter geneVariations in the ospB gene of Borrelia burgdorferi result in differences in monoclonal antibody reactivity and in production of escape variantsA bactericidal antibody to Borrelia burgdorferi is directed against a variable region of the OspB protein.Linear- and circular-plasmid copy numbers in Borrelia burgdorferi.The role of Borrelia burgdorferi outer surface proteinsAntibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterizationOuter surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine.Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease.OspB antibody prevents Borrelia burgdorferi colonization of Ixodes scapularis.Use of the "blue halo" assay in the identification of genes encoding exported proteins with cleavable signal peptides: cloning of a Borrelia burgdorferi plasmid gene with a signal peptide.Selection of an escape variant of Borrelia burgdorferi by use of bactericidal monoclonal antibodies to OspB.Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector.Correlation between molecular size of the surface array protein and morphology and antigenicity of the Campylobacter fetus S layer.Characterization of a Borrelia burgdorferi dnaJ homolog.Characterization of a chromosomal gene and the antigen it expresses from the Lyme disease agent, Borrelia burgdorferi.Plasmid analysis of Borrelia burgdorferi, the Lyme disease agentIdentification of Borrelia burgdorferi and B. hermsii using DNA hybridization probes.The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal geneComparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice.Laboratory aspects of Lyme borreliosis.
P2860
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P2860
Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 1986
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Organization of genes encoding ...... a single transcriptional unit
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Organization of genes encoding ...... a single transcriptional unit.
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type
label
Organization of genes encoding ...... a single transcriptional unit
@en
Organization of genes encoding ...... a single transcriptional unit.
@nl
prefLabel
Organization of genes encoding ...... a single transcriptional unit
@en
Organization of genes encoding ...... a single transcriptional unit.
@nl
P2093
P2860
P1476
Organization of genes encoding ...... a single transcriptional unit
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P2093
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P304
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P577
1986-10-01T00:00:00Z