Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection.
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Immunopathology of Schistosoma mansoni infectionThe Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite InfectionLow transformation growth factor-β1 production and collagen synthesis correlate with the lack of hepatic periportal fibrosis development in undernourished mice infected with Schistosoma mansoni.CD4+ T-cell receptor V beta usage during the immune response to Schistosoma mansoni.Egg laying is delayed but worm fecundity is normal in SCID mice infected with Schistosoma japonicum and S. mansoni with or without recombinant tumor necrosis factor alpha treatmentTh1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection.Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni.A novel 62-kilodalton egg antigen from Schistosoma mansoni induces a potent CD4(+) T helper cell response in the C57BL/6 mouse.Polarization of the immune response to the single immunodominant epitope of p38, a major Schistosoma mansoni egg antigen, generates Th1- or Th2-type cytokines and granulomas.Schistosoma mansoni phosphoenolpyruvate carboxykinase, a novel egg antigen: immunological properties of the recombinant protein and identification of a T-cell epitopeSoluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection.Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidaseDexamethasone, a drug for attenuation of Schistosoma mansoni infection morbiditySoluble intercellular adhesion molecules in human schistosomiasis: correlations with disease severity and decreased responsiveness to egg antigens.Administration of purified anti-L3T4 monoclonal antibody impairs the resistance of mice to Listeria monocytogenes infection.Deficiency of interleukin-2 production upon addition of soluble egg antigen to cultures of isolated hepatic granulomas or hepatic granuloma cells from mice infected with Schistosoma japonicum.Characterization of protective T cells in the acquired response to Leishmania donovani in genetically determined cure (H-2b) and noncure (H-2d) mouse strains.Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis.Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice.T-lymphocyte responsiveness in murine schistosomiasis mansoni is dependent upon the adhesion molecules intercellular adhesion molecule-1, lymphocyte function-associated antigen-1, and very late antigen-4.Regulation of granulomatous inflammation in experimental models of schistosomiasisEvaluation of CD4(+)/CD8(+) status and urinary tract infections associated with urinary schistosomiasis among some rural Nigerians.In situ analysis of B7-2 costimulatory, major histocompatibility complex class II, and adhesion molecule expression in schistosomal egg granulomas.Immunopathology of schistosomiasisEndogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology.Chronic schistosome infection leads to modulation of granuloma formation and systemic immune suppression.The schistosoma granuloma: friend or foe?Utilization of fractionated soluble egg antigens reveals selectively modulated granulomatous and lymphokine responses during murine schistosomiasis mansoni.Induction and regulation of pathogenic Th17 cell responses in schistosomiasis.Role of L3T4+ T cells in host defense against Histoplasma capsulatumDeficiency of interleukin-2 activity upon addition of soluble egg antigen to cultures of spleen cells from mice infected with Schistosoma japonicum.Macrophage progenitor cell and colony-stimulating factor production during granulomatous schistosomiasis mansoni in mice.Establishment and characterization of an antigen-specific T-cell line from liver granulomas of Schistosoma mansoni-infected miceImpaired lymphocyte profile in schistosomiasis patients with periportal fibrosis.HLA class II polymorphism influences onset and severity of pathology in Schistosoma mansoni-infected transgenic mice.Interleukin-4 receptor alpha chain and STAT6 signaling inhibit gamma interferon but not Th2 cytokine expression within schistosome granulomas.Partial characterization of a fibroblast-stimulating factor produced by cloned murine T lymphocytes.Curse of schistosomiasis on Egyptian liver.Schistosoma "Eggs-Iting" the Host: Granuloma Formation and Egg Excretion
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Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1986
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@en
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@nl
type
label
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@en
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@nl
prefLabel
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@en
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@nl
P2860
P921
P1476
Anti-L3T4 antibody treatment s ...... Schistosoma mansoni infection.
@en
P2093
P2860
P304
P407
P577
1986-12-01T00:00:00Z