Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function. - Wikidata - awgldk - TriplyDB

Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function.

Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function.

http://www.wikidata.org/entity/Q37021785

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Dinosaurs and ancient civilizations: reflections on the treatment of cancer Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation UVB irradiation regulates ERK1/2- and p53-dependent thrombomodulin expression in human keratinocytes Resveratrol inhibits cisplatin-induced epithelial-to-mesenchymal transition in ovarian cancer cell lines Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells.Cancer/testis antigen CAGE exerts negative regulation on p53 expression through HDAC2 and confers resistance to anti-cancer drugs.Notch1 binds and induces degradation of Snail in hepatocellular carcinoma.Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression Snail transcription factor negatively regulates maspin tumor suppressor in human prostate cancer cells.Ras puts the brake on doxorubicin-mediated cell death in p53-expressing cells Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1 Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1-PUMA pathway The interconnectedness of cancer cell signaling.Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.NF2 blocks Snail-mediated p53 suppression in mesothelioma.KSHV-Mediated Regulation of Par3 and SNAIL Contributes to B-Cell Proliferation Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.Systems analysis reveals a transcriptional reversal of the mesenchymal phenotype induced by SNAIL-inhibitor GN-25.The War on Cancer rages on.Extracellular p53 fragment re-enters K-Ras mutated cells through the caveolin-1 dependent early endosomal system.Major heat shock protein Hsp72 controls oncogene-induced senescence.Oncogenic roles of EMT-inducing transcription factors.Evidence of a prion-like transmission of p53 amyloid in Saccharomyces cerevisiae.Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease.A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.Domain analysis of the Nematostella vectensis SNAIL ortholog reveals unique nucleolar localization that depends on the zinc-finger domains.Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths.New functions for the Snail family of transcription factors: Two-faced proteins.Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail.Interleukin-32 expression is associated with a poorer prognosis in head and neck squamous cell carcinoma.Snail1 transcription factor controls telomere transcription and integrity.Silencing the Snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells.p53, secreted by K-Ras-Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker.Polycomb group proteins: New targets of anti-cancer therapy.Chalcone Derivatives 4'-Amino-1-Naphthyl-Chalcone (D14) and 4'-Amino-4-Methyl-1-Naphthyl-Chalcone (D15) Suppress Migration and Invasion of Osteosarcoma Cells Mediated by p53 Regulating EMT-Related Genes

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P2860

Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function.

http://www.wikidata.org/entity/Q37021785

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Blocking of p53-Snail binding, ...... s p53 expression and function.

@en

Blocking of p53-Snail binding, ...... s p53 expression and function.

@nl

type

label

Blocking of p53-Snail binding, ...... s p53 expression and function.

@en

Blocking of p53-Snail binding, ...... s p53 expression and function.

@nl

prefLabel

Blocking of p53-Snail binding, ...... s p53 expression and function.

@en

Blocking of p53-Snail binding, ...... s p53 expression and function.

@nl

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Blocking of p53-Snail binding, ...... s p53 expression and function.

@en

P2093

Bum-Joon Park

http://www.w3.org/2001/XMLSchema#string

Ho Sung Kang

http://www.w3.org/2001/XMLSchema#string

Nam-Chul Ha

http://www.w3.org/2001/XMLSchema#string

Su-Jin Lee

http://www.w3.org/2001/XMLSchema#string

Sun-Hye Lee

http://www.w3.org/2001/XMLSchema#string

Yeon Sang Jung

http://www.w3.org/2001/XMLSchema#string

Yongbin Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

p53, the cellular gatekeeper for growth and division

Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

Targeting RAS signalling pathways in cancer therapy

Flavonols and pancreatic cancer risk: the multiethnic cohort study

Divorcing ARF and p53: an unsettled case

P304

22-31, 6p following 31

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scholarly article

P356

10.1593/NEO.81006

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1

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11

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2009-01-01T00:00:00Z

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23688896

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19107228

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P932

2606115

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