A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells.
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An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro.Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling.Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma.Growth inhibitory effect of β-eudesmol on cholangiocarcinoma cells and its potential suppressive effect on heme oxygenase-1 production, STAT1/3 activation, and NF-κB downregulation.The effect of miR-146a on STAT1 expression and apoptosis in acute lymphoblastic leukemia Jurkat cells.Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development.Two novel SHP-1 agonists, SC-43 and SC-78, are more potent than regorafenib in suppressing the in vitro stemness of human colorectal cancer cells
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P2860
A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 February 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A novel small molecule STAT3 i ...... colon and liver cancer cells.
@en
A novel small molecule STAT3 i ...... colon and liver cancer cells.
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type
label
A novel small molecule STAT3 i ...... colon and liver cancer cells.
@en
A novel small molecule STAT3 i ...... colon and liver cancer cells.
@nl
prefLabel
A novel small molecule STAT3 i ...... colon and liver cancer cells.
@en
A novel small molecule STAT3 i ...... colon and liver cancer cells.
@nl
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A novel small molecule STAT3 i ...... colon and liver cancer cells.
@en
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Chenglong Li
Chongqiang Zhao
Cuntai Zhang
Jiayuh Lin
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P304
12917-12926
P356
10.18632/ONCOTARGET.7338
P407
P577
2016-02-11T00:00:00Z