Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development.
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Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signallingRoles of BMP signaling pathway in lip and palate developmentSignaling networks in palate developmentCryptic patterning of avian skin confers a developmental facility for loss of neck featheringThe p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migrationGadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expressionBMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathwaysPhenotypic and evolutionary implications of modulating the ERK-MAPK cascade using the dentition as a modelEpithelial-specific requirement of FGFR2 signaling during tooth and palate development.Functional role of TGF-β receptors during palatal fusion in vitroTranscription factor FoxO1 is essential for enamel biomineralization.Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis.Transforming growth factor Beta 3 is required for excisional wound repair in vivop38α MAPK is required for tooth morphogenesis and enamel secretionSMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development.Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retinaTak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development.Palate morphogenesis: current understanding and future directions.Smad4-Shh-Nfic signaling cascade-mediated epithelial-mesenchymal interaction is crucial in regulating tooth root developmentWnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.Palatogenesis: morphogenetic and molecular mechanisms of secondary palate developmentBmp signaling regulates a dose-dependent transcriptional program to control facial skeletal developmentModulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.The mechanism of TGF-β signaling during palate development.IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion.Induction of palate epithelial mesenchymal transition by transforming growth factor β3 signaling.Cellular and Molecular Mechanisms of PalatogenesisMolecular signaling along the anterior-posterior axis of early palate development.Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice.Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.Mice with Tak1 deficiency in neural crest lineage exhibit cleft palate associated with abnormal tongue development.Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male MiceNicotine Exposure During Pregnancy Results in Persistent Midline Epithelial Seam With Improper Palatal FusionCTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development.Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation.Noncanonical transforming growth factor β (TGFβ) signaling in cranial neural crest cells causes tongue muscle developmental defects.Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence.Fate of HERS during tooth root development
P2860
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P2860
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@en
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@nl
type
label
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@en
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@nl
prefLabel
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@en
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@nl
P2093
P2860
P1433
P1476
Ectodermal Smad4 and p38 MAPK ...... tooth and palate development.
@en
P2093
Chuxia Deng
Pablo Bringas
Yoshihiro Ito
P2860
P304
P356
10.1016/J.DEVCEL.2008.06.004
P407
P577
2008-08-01T00:00:00Z