Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells.
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Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with DysregulationPeptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary GlandRole of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migrationProtein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.Reprogramming during epithelial to mesenchymal transition under the control of TGFβDetection and identification of protein citrullination in complex biological systemsHistone deacetylase HDA6 enhances brassinosteroid signaling by inhibiting the BIN2 kinase.A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22Autoantibodies to posttranslational modifications in rheumatoid arthritis.Citrullinated Autoantigens: From Diagnostic Markers to Pathogenetic Mechanisms.Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseasesPAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling.Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.Glycogen synthase kinase 3 in Wnt signaling pathway and cancer.A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination.Recent advances in understanding the cellular roles of GSK-3.Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis.Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer.Rheumatoid arthritis and citrullination.Adipocytes induce distinct gene expression profiles in mammary tumor cells and enhance inflammatory signaling in invasive breast cancer cells.How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress-Therapeutic Implications.Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix
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Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
@en
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
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type
label
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
@en
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
@nl
prefLabel
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
@en
Dysregulation of PAD4-mediated ...... sition in breast cancer cells.
@nl
P2093
P2860
P356
P1476
Dysregulation of PAD4-mediated ...... nsition in breast cancer cells
@en
P2093
Anthony M C Brown
Antonia Patsialou
Benjamin A Garcia
C David Allis
C Theresa Vincent
John S Condeelis
Joseph J Wakshlag
Scott A Coonrod
Sonja C Stadler
Sunish Mohanan
P2860
P304
11851-11856
P356
10.1073/PNAS.1308362110
P407
P577
2013-07-01T00:00:00Z