Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
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Immunotherapy for tularemiaSubversion of host recognition and defense systems by Francisella sppAn Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory PathogensEffective, broad spectrum control of virulent bacterial infections using cationic DNA liposome complexes combined with bacterial antigensFine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensisHost-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.The presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo.A tolC mutant of Francisella tularensis is hypercytotoxic compared to the wild type and elicits increased proinflammatory responses from host cells.CpG oligodeoxyribonucleotides protect mice from Burkholderia pseudomallei but not Francisella tularensis Schu S4 aerosols.Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infectionGroEL and lipopolysaccharide from Francisella tularensis live vaccine strain synergistically activate human macrophagesIdentification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets.Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo.Mucosal immunotherapy for protection from pneumonic infection with Francisella tularensisRestricted cytosolic growth of Francisella tularensis subsp. tularensis by IFN-gamma activation of macrophagesFrancisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine productionLong lived protection against pneumonic tularemia is correlated with cellular immunity in peripheral, not pulmonary, organs.Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemiaHost-pathogen interactions and immune evasion strategies in Francisella tularensis pathogenicityDotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicityLow dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination.Virulent Francisella tularensis destabilize host mRNA to rapidly suppress inflammation.Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensisFrancisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responsesSuccessful protection against tularemia in C57BL/6 mice is correlated with expansion of Francisella tularensis-specific effector T cells.The subversion of the immune system by francisella tularensis.Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella speciesA Francisella tularensis locus required for spermine responsiveness is necessary for virulence.Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cellsFrancisella tularensis RipA protein topology and identification of functional domains.Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist.Enhanced detection of Rift Valley fever virus using molecular assays on whole blood samplesIdentification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response.Proteomic analysis of bronchoalveolar lavage fluid proteins from mice infected with Francisella tularensis ssp. novicida.Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis.Antioxidant Defenses of Francisella tularensis Modulate Macrophage Function and Production of Proinflammatory Cytokines.B1a cells enhance susceptibility to infection with virulent Francisella tularensis via modulation of NK/NKT cell responses.Metabolic Reprogramming of Host Cells by Virulent Francisella tularensis for Optimal Replication and Modulation of Inflammation.F. novicida-Infected A. castellanii Does Not Enhance Bacterial Virulence in Mice.Mechanisms of Francisella tularensis intracellular pathogenesis.
P2860
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P2860
Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@en
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@nl
type
label
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@en
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@nl
prefLabel
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@en
Direct and indirect impairment ...... rancisella tularensis Schu S4.
@nl
P2860
P356
P1476
Direct and indirect impairment ...... Francisella tularensis Schu S4
@en
P2093
Catharine M Bosio
Jennifer C Chase
P2860
P304
P356
10.1128/IAI.00879-08
P407
P50
P577
2008-11-03T00:00:00Z