Prion strain targeting independent of strain-specific neuronal tropism.
about
The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseasePrion formation, but not clearance, is supported by protein misfolding cyclic amplification.Coinfecting prion strains compete for a limiting cellular resource.Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infectionTracking protein aggregate interactions.Striatal pathology underlies prion infection-mediated hyperactivity in mice.Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype.PrPSc formation and clearance as determinants of prion tropism.Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins.Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathwaysPrion propagation and toxicity occur in vitro with two-phase kinetics specific to strain and neuronal type.Prion protein glycosylation is not required for strain-specific neurotropism.Specificity, Size, and Frequency of Spaces That Characterize the Mechanism of Bulk Transepithelial Transport of Prions in the Nasal Cavities of Hamsters and Mice.Atypical and classical forms of the disease-associated state of the prion protein exhibit distinct neuronal tropism, deposition patterns, and lesion profiles.RNA-binding proteins associated molecular mechanisms of motor neuron degeneration pathogenesis.Incongruity between Prion Conversion and Incubation Period following Coinfection.Disease characteristics of bovine spongiform encephalopathy following inoculation into mice via three different routes.Flow Cytometric Detection of PrPSc in Neurons and Glial Cells from Prion-Infected Mouse Brains.
P2860
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P2860
Prion strain targeting independent of strain-specific neuronal tropism.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Prion strain targeting independent of strain-specific neuronal tropism.
@en
Prion strain targeting independent of strain-specific neuronal tropism.
@nl
type
label
Prion strain targeting independent of strain-specific neuronal tropism.
@en
Prion strain targeting independent of strain-specific neuronal tropism.
@nl
prefLabel
Prion strain targeting independent of strain-specific neuronal tropism.
@en
Prion strain targeting independent of strain-specific neuronal tropism.
@nl
P2860
P50
P356
P1433
P1476
Prion strain targeting independent of strain-specific neuronal tropism.
@en
P2860
P356
10.1128/JVI.01745-08
P407
P577
2008-10-29T00:00:00Z