Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I
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Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor)Role of receptor tyrosine kinases and their ligands in glioblastoma.Episomal vectors for gene expression in mammalian cells.Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo.The contradictions of the insulin-like growth factor 1 receptor.MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3).Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationRescue of MHC-1 antigen processing machinery by down-regulation in expression of IGF-1 in human glioblastoma cells.PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivoGene therapy of murine teratocarcinoma: separate functions for insulin-like growth factors I and II in immunogenicity and differentiation.Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468.Antigen-presenting cell engineering. The molecular toolboxInterleukin-1 beta-modulated gene expression in immortalized human chondrocytes.Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells.Molecular biology of human gliomas.Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptorC/EBPbeta regulates body composition, energy balance-related hormones and tumor growthCritical prosurvival roles for C/EBP beta and insulin-like growth factor I in macrophage tumor cells.Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo.Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy.Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cellsGenetic blockade of insulin-like growth factor-1 receptor via recombinant adenovirus in lung cancer can be enhanced by the histone deacetylase inhibitor, vorinostat.CD21-mediated entry and stable infection by Epstein-Barr virus in canine and rat cells.Failure of the bovine papillomavirus to transform mouse embryo fibroblasts with a targeted disruption of the insulin-like growth factor I receptor genes.Physiology and gene expression characteristics of carcinogen-initiated and tumor-transformed glial progenitor cells derived from the CNS of methylnitrosourea (MNU)-treated Sprague-Dawley rats.Insulin-like growth factors in central nervous system tumors.Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATPFrom proopiomelanocortin to cancer. Possible role of convertases in neoplasia.Long-term replication of Epstein-Barr virus-derived episomal vectors in the rodent cells.Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma.Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor.Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth.Human glioma cells transformed by IGF-I triple helix technology show immune and apoptotic characteristics determining cell selection for gene therapy of glioblastoma.Receptor-mediated delivery of an antisense gene to human brain cancer cells.Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer.IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells.Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas.PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines
P2860
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P2860
Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Loss of tumorigenicity of rat ...... f insulin-like growth factor I
@en
Loss of tumorigenicity of rat ...... insulin-like growth factor I.
@nl
type
label
Loss of tumorigenicity of rat ...... f insulin-like growth factor I
@en
Loss of tumorigenicity of rat ...... insulin-like growth factor I.
@nl
prefLabel
Loss of tumorigenicity of rat ...... f insulin-like growth factor I
@en
Loss of tumorigenicity of rat ...... insulin-like growth factor I.
@nl
P2093
P2860
P356
P1476
Loss of tumorigenicity of rat ...... f insulin-like growth factor I
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.11.4874
P407
P577
1992-06-01T00:00:00Z