Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468.
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The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionSerological identification and expression analysis of gastric cancer-associated genesAn update of biochemical markers of hepatocellular carcinomaStructure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activitiesProgranulin: normal function and role in neurodegenerationCartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferationThe Evolution of the Secreted Regulatory Protein ProgranulinInhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK4 and inactivation of MMP-2Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis.GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cellsmiR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative diseaseGranulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix proteinGP88 (progranulin): a novel tissue and circulating biomarker for non-small cell lung carcinoma.Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA bindingGEP, a local growth factor, is critical for odontogenesis and amelogenesis.Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor).Progranulin is a chemoattractant for microglia and stimulates their endocytic activity.Increased Circulating Level of the Survival Factor GP88 (Progranulin) in the Serum of Breast Cancer Patients When Compared to Healthy SubjectsGranulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer.Progranulin: a growth factor, a novel TNFR ligand and a drug targetDisruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice.GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation.hsDNA groove binding, photocatalytic activity, and in vitro breast and colon cancer cell reducing function of greener SeNPs.Correlation of granulin expression in intracranial meningiomas to clinical parameters.Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration.Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma.Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth.Determination of GP88 (progranulin) expression in breast tumor biopsies improves the risk predictive value of the Nottingham Prognostic Index.Proepithelin is an autocrine growth factor for bladder cancerADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin.Proteoglycans: master modulators of paracrine fibroblast-carcinoma cell interactions.Growth factors as active participants in carcinogenesis: a perspective.Role of progranulin as a biomarker for Alzheimer's disease.The role of ADAMTSs in arthritisCellular effects of progranulin in health and disease.Structure, function, and mechanism of progranulin; the brain and beyond.Progranulin: a novel regulator of gastrointestinal cancer progression.The oncogene Nup98-HOXA9 induces gene transcription in myeloid cells.
P2860
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P2860
Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@ast
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@en
type
label
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@ast
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@en
prefLabel
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@ast
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@en
P2860
P356
P1476
Inhibition of PC cell-derived ...... arcinoma cell line MDA-MB-468.
@en
P2860
P304
P356
10.1073/PNAS.97.8.3993
P407
P577
2000-04-01T00:00:00Z