The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.
about
Multiple drug resistance-associated protein 4 (MRP4), prostaglandin transporter (PGT), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancerIndividualization of antiretroviral therapy--pharmacogenomic aspectPharmacogenomic discovery using cell-based modelsABC Transport Proteins in Cardiovascular Disease-A Brief Summary.Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of AsthmaticsFluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.Runs of homozygosity and population history in cattleFunctional hot spots in human ATP-binding cassette transporter nucleotide binding domains.Influence of PTGS1, PTGFR, and MRP4 genetic variants on intraocular pressure response to latanoprost in Chinese primary open-angle glaucoma patients.Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infectionABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohortA pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome.Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice.Few Drugs Display Flip-Flop Pharmacokinetics and These Are Primarily Associated with Classes 3 and 4 of the BDDCSEffect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.The ABCC4 membrane transporter modulates platelet aggregation.MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.ABCC4 Is a Determinant of Cytarabine-Induced Cytotoxicity and Myelosuppression.Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expressionABCC4 is regulated by microRNA-124a and microRNA-506Drug transporter pharmacogenetics in nucleoside-based therapies.Pharmacogenetics of drug transporters in the enterohepatic circulation.Renal transport of organic anions and cations.Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions.In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants.The role of the SHH gene in prostate cancer cell resistance to paclitaxel.Pharmacokinetics and pharmacogenomics of β-lactam-induced neutropenia.Multidrug resistance protein 4 is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogues.Plasma and intracellular exposure to ganciclovir in adult renal transplant recipients: is there an association with haematological toxicity?PharmGKB summary: zidovudine pathwayPredictable difficulty or difficulty to predict.The effect of carboxylesterase 1 (CES1) polymorphisms on the pharmacokinetics of oseltamivir in humans.Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men.ABCC4 functional SNP in the 3' splice acceptor site of exon 8 (G912T) is associated with unfavorable clinical outcome in children with acute lymphoblastic leukemia.
P2860
Q26828414-126578C7-6858-440D-9596-06CCCB112AF7Q28070574-61DC83AF-3F5D-48E6-8FBD-684430A62EE2Q28392982-EA5EF649-DD7D-490E-94E7-D8A54D8B80EFQ30313271-32E3585D-83D9-488D-BB23-C3858A166D13Q30419764-0C4D1FDC-B698-4E8A-BC7A-FE5434D35C8DQ30728815-E6F963E8-3B0F-46EA-8E9C-0B8898C75D12Q33714593-88ACB800-B8FC-4964-9522-E6FC296D51F0Q33808822-8D6B8333-942E-4DD3-82DF-BC15457E8AEDQ34058706-548EA920-F12A-436D-A987-AF857F5ABA3EQ34071782-C2224E2E-E1E1-45C3-AE2F-B2BBF9C97277Q34378130-17896354-194D-4948-BABA-8FC529BBBF6FQ34423739-B63FA93A-4665-40A1-ABE1-14DB47E4E7B9Q34444557-6E2345CD-3C9F-4E23-9B70-DD24C59D1F82Q34481359-1DD716AD-6709-4D4B-A230-6E11CB127A4EQ34571645-C2FBDA2A-2D90-47D1-A585-B4D8E81CA8ABQ35091774-BA85F1A9-6CD9-404C-827C-3117EFE5F7CCQ35775875-80F4E164-B983-43F1-968D-4F5A059D8315Q35776279-3BA1E861-3F09-449E-8E68-1761937B9706Q35800047-BD88D373-D544-44AF-A579-9DC55811FA98Q35952140-334712AD-49AE-4057-8D8D-CCADD5AD44C7Q36018600-8470FB24-AE9C-4C39-AD66-7D642FAF9AFBQ36274845-8F36DC1D-8F59-495F-B015-54115E3D49EFQ36766565-D81C8FC5-52CE-4B06-910D-F1A7F5417AAAQ36998913-30168C2E-3010-4FB9-83C5-E293AA27FBEEQ37311836-71E5C57D-6D16-4140-B0B0-C09B8ECF84CEQ37590000-B81E112B-43D2-411E-A026-0677FFFC6388Q37760954-A4244223-BCD1-422A-96C7-3811A1F96B26Q37880875-A17141FB-D38F-4360-ABA3-90B4CB0679DAQ38111725-BA8AAE9B-AF38-4243-ABE2-36C155AF1D0AQ38160088-CE6E1AF2-3B1D-4AE3-9A91-FEDA97F7558BQ38838936-1A35D2F7-C78B-415B-AA3C-BB1D67374DAEQ38985293-4A051298-2035-468B-AF98-96A053EFDF0CQ40728370-19075135-581E-4A7F-B649-C51007685D99Q40771426-2B069558-DE26-4FC8-99E6-92C224EA7314Q40922185-13F435AB-94C4-4A09-B7DE-97F098EF7F87Q41474530-6BC0145F-9766-46C6-A783-4AE9B3682B87Q42643024-89BB9956-9025-4891-83F4-7DD2CBFAD520Q43882150-DA83238D-6407-4DD8-904E-768A0CA45E5DQ48524891-0E8771B9-E1AF-4088-9795-10063F866DC6Q50976201-01B2F2EA-F9B7-4FD9-B4A7-1423A8EEF272
P2860
The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The human multidrug resistance ...... of a highly polymorphic gene.
@en
The human multidrug resistance ...... of a highly polymorphic gene.
@nl
type
label
The human multidrug resistance ...... of a highly polymorphic gene.
@en
The human multidrug resistance ...... of a highly polymorphic gene.
@nl
prefLabel
The human multidrug resistance ...... of a highly polymorphic gene.
@en
The human multidrug resistance ...... of a highly polymorphic gene.
@nl
P2093
P2860
P356
P1476
The human multidrug resistance ...... of a highly polymorphic gene.
@en
P2093
Conrad C Huang
Deanna L Kroetz
Doug Stryke
Kathleen M Giacomini
Leslie W Chinn
Michiko Kawamoto
Susan J Johns
Thomas E Ferrin
P2860
P304
P356
10.1124/JPET.108.136523
P407
P577
2008-03-25T00:00:00Z