STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6.
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Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas.STAT3 and epithelial-mesenchymal transitions in carcinomasDeficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolismThe Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus.STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b.The transcriptional modulator BCL6 as a molecular target for breast cancer therapyReciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3.Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypesICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.Circadian disruption-induced microRNAome deregulation in rat mammary gland tissues.Mechanisms of Jak/STAT signaling in immunity and diseaseHuman Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseLocal and systemic factors and implantation: what is the evidence?All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.Protein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis.Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.Mutual interaction between BCL6 and miRNAs contributing to the pathogenesis of various cancers.KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance.Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2.BCL6--regulated by AhR/ARNT and wild-type MEF2B--drives expression of germinal center markers MYBL1 and LMO2.Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target.STAT5-Interacting Proteins: A Synopsis of Proteins that Regulate STAT5 Activity.ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T CellsWhole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation.Musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity.FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node.Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells.Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia.The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
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P2860
STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@en
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@nl
type
label
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@en
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@nl
prefLabel
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@en
STAT5 outcompetes STAT3 to reg ...... ranscriptional modulator BCL6.
@nl
P2093
P2860
P356
P1476
STAT5 outcompetes STAT3 to reg ...... transcriptional modulator BCL6
@en
P2093
David A Frank
Erik A Nelson
Guo-Cheng Yuan
Jennifer E Yeh
Sarah R Walker
P2860
P304
P356
10.1128/MCB.01620-12
P407
P50
P577
2013-05-28T00:00:00Z