The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
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Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networksZNF703 gene amplification at 8p12 specifies luminal B breast cancerComprehensive molecular portraits of human breast tumoursRetinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesThe other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axisRetinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventionsPost-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cellsBiomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosisEfficacy of neoadjuvant Cisplatin in triple-negative breast cancerPhenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancerThe clonal and mutational evolution spectrum of primary triple-negative breast cancersRb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.A data similarity-based strategy for meta-analysis of transcriptional profiles in cancer.Web-based interrogation of gene expression signatures using EXALT.Tumorigenic WAP-T mouse mammary carcinoma cells: a model for a self-reproducing homeostatic cancer cell system.Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival.αB-crystallin promotes oncogenic transformation and inhibits caspase activation in cells primed for apoptosis by Rb inactivation.p16INK4a expression in basal-like breast carcinoma.Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancersCoregulation of FANCA and BRCA1 in human cellsThe retinoblastoma tumor suppressor pathway modulates the invasiveness of ErbB2-positive breast cancer.Molecular insights on basal-like breast cancer.The neutrophil elastase inhibitor elafin triggers rb-mediated growth arrest and caspase-dependent apoptosis in breast cancer.The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developmentsANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.A Novel Subset of Human Tumors That Simultaneously Overexpress Multiple E2F-responsive Genes Found in Breast, Ovarian, and Prostate CancersCooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution.Targeting breast cancer stem cells.Micro-scale genomic DNA copy number aberrations as another means of mutagenesis in breast cancer.Hippo pathway mediates resistance to cytotoxic drugs.Minireview: Basal-like breast cancer: from molecular profiles to targeted therapiesSystems biology and genomics of breast cancer.Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers.Chemotherapy induced microsatellite instability and loss of heterozygosity in chromosomes 2, 5, 10, and 17 in solid tumor patients.RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response.Genes dysregulated to different extent or oppositely in estrogen receptor-positive and estrogen receptor-negative breast cancers.An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Pathologic progression of mammary carcinomas in a C3(1)/SV40 T/t-antigen transgenic rat model of human triple-negative and Her2-positive breast cancer.
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The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 September 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The functional loss of the ret ...... nd luminal B breast carcinomas
@en
The functional loss of the ret ...... d luminal B breast carcinomas.
@nl
type
label
The functional loss of the ret ...... nd luminal B breast carcinomas
@en
The functional loss of the ret ...... d luminal B breast carcinomas.
@nl
prefLabel
The functional loss of the ret ...... nd luminal B breast carcinomas
@en
The functional loss of the ret ...... d luminal B breast carcinomas.
@nl
P2093
P2860
P356
P1476
The functional loss of the ret ...... nd luminal B breast carcinomas
@en
P2093
Jason I Herschkowitz
Xiaping He
P2860
P2888
P356
10.1186/BCR2142
P577
2008-09-09T00:00:00Z
P5875
P6179
1005607697