Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. - Wikidata - awgldk - TriplyDB

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.

http://www.wikidata.org/entity/Q33742688

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An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes Genetically engineered ERα-positive breast cancer mouse models.A murine preclinical syngeneic transplantation model for breast cancer precision medicine.In vivo models in breast cancer research: progress, challenges and future directions.Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis.A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State Cholesterol and breast cancer pathophysiology.Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer.Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models.Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer.Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer.Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer.A Long-Lived Luminal Subpopulation Enriched with Alveolar Progenitors Serves as Cellular Origin of Heterogeneous Mammary Tumors.Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet.Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model.Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress.The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.The origin of breast tumor heterogeneity.Increased metastasis with loss of E2F2 in Myc-driven tumors.Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and Metastasis Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes.Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer.Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.RANKL/RANK control Brca1 mutation-driven mammary tumors.Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes.In vivo Reprogramming of Cancer Metabolism by MYC.Illuminating breast cancer invasion: diverse roles for cell-cell interactions.Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu.Mouse Models of Breast Cancer Share Amplification and Deletion Events with Human Breast Cancer.One microenvironment does not fit all: heterogeneity beyond cancer cells.Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.

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Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.

http://www.wikidata.org/entity/Q33742688

description

2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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Transcriptomic classification ...... es human subtype counterparts.

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Transcriptomic classification ...... es human subtype counterparts.

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Transcriptomic classification ...... es human subtype counterparts.

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Transcriptomic classification ...... es human subtype counterparts.

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Transcriptomic classification ...... es human subtype counterparts.

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Transcriptomic classification ...... es human subtype counterparts.

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

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