The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
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Lessons from C. elegans: signaling pathways for longevityAlpha-Ketoglutarate: Physiological Functions and ApplicationsLong live FOXO: unraveling the role of FOXO proteins in aging and longevityA Genetic Cascade of let-7-ncl-1-fib-1 Modulates Nucleolar Size and rRNA Pool in Caenorhabditis elegansHIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegansThe Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycinLifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegansETS-4 is a transcriptional regulator of life span in Caenorhabditis elegansManipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental responseMechanisms of aging-related proteinopathies in Caenorhabditis elegansTranscriptional and epigenetic regulation of autophagy in agingTOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxOHaploinsufficiency of akt1 prolongs the lifespan of miceC. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan ExtensionGlobal Proteomics Analysis of the Response to Starvation in C. elegansRVB1/RVB2: running rings around molecular biology.A metabolic signature of long life in Caenorhabditis elegansA two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.Dynamic chromatin organization during foregut development mediated by the organ selector gene PHA-4/FoxAAçai palm fruit (Euterpe oleracea Mart.) pulp improves survival of flies on a high fat dietGenetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans.The new biology of ageing.With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in agingdrr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans.Dietary restriction and aging, 2009.Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans.RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span.The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegansRole of TOR signaling in aging and related biological processes in Drosophila melanogasterConverging pathways in lifespan regulationA Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans.Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans.S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cellsIntestinal apical polarity mediates regulation of TORC1 by glucosylceramide in C. elegansThe nucleolus of Caenorhabditis elegans.Mitochondrial deficiency: a double-edged sword for aging and neurodegeneration.Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
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The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@en
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@nl
type
label
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@en
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@nl
prefLabel
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@en
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
@nl
P2860
P1433
P1476
The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging
@en
P2093
Karyn L Sheaffer
P2860
P304
P356
10.1016/J.CUB.2008.07.097
P407
P577
2008-09-01T00:00:00Z