Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin.
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Protein C inhibitor secreted from activated platelets efficiently inhibits activated protein C on phosphatidylethanolamine of platelet membrane and microvesiclesHuman Protein ZThrombomodulin is present in human plasma and urineDeficiency of protein C in congenital thrombotic diseaseThe structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAsHuman platelets contain and secrete osteonectin, a major protein of mineralized boneThermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loopsDeficiency of protein C inhibitor in combined factor V/VIII deficiency diseaseOral anticoagulants: pharmacodynamics, clinical indications and adverse effectsEstimation of the distance between the divalent cation binding site of des-1-41-light chain-activated bovine plasma protein C and a nitroxide spin label attached to the active-site serine residueCharacterization of a cDNA coding for human protein CPlasma levels of activated protein C-protein C inhibitor complex in patients with hypercoagulable states.Trends in physiological coagulation factors in Japanese patients receiving novel oral anticoagulantsTourniquet-applied upper limb orthopaedic surgery results in increased inflammation and changes to leukocyte, coagulation and endothelial markers.Refining anti-inflammatory therapy strategies for bronchopulmonary dysplasia.Antithrombotic effects of thrombin-induced activation of endogenous protein C in primates.Activated factor V is a cofactor for the activation of factor XI by thrombin in plasma.Mechanism of cephalosporin-induced hypoprothrombinemia: relation to cephalosporin side chain, vitamin K metabolism, and vitamin K status.Carboxypeptidase U at the interface between coagulation and fibrinolysis.Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population.Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation.Platelet factor 4 inhibits thrombomodulin-dependent activation of thrombin-activatable fibrinolysis inhibitor (TAFI) by thrombinRelationship between protein C antigen and anticoagulant activity during oral anticoagulation and in selected disease statesDetection of protein C activation in humansHemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study.Suppression of hemostatic system activation by oral anticoagulants in the blood of patients with thrombotic diatheses.Evolution and organization of the human protein C gene.The characterization of mice with a targeted combined deficiency of protein c and factor XI.Extrahepatic expression and regulation of protein C in the mouse.Enhancement of rabbit protein S anticoagulant cofactor activity in vivo by modulation of the protein S C4B binding protein interaction.Murine lymphoid procoagulant activity induced by bacterial lipopolysaccharide and immune complexes is a monocyte prothrombinaseCloning and sequencing of liver cDNA coding for bovine protein C.Drotrecogin alfa (activated) in the treatment of severe sepsis.Familial venous thrombosis.The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels.Drotrecogin alpha (activated): the treatment for severe sepsis?Evidence of normal functional levels of activated protein C inhibitor in combined Factor V/VIII deficiency disease.The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.N-glycosylation microheterogeneity and site occupancy of an Asn-X-Cys sequon in plasma-derived and recombinant protein C.Human coagulation factor Va is a cofactor for the activation of protein C.
P2860
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P2860
Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@en
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@nl
type
label
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@en
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@nl
prefLabel
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@en
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@nl
P2860
P356
P1476
Human plasma protein C: isolat ...... activation by alpha-thrombin.
@en
P2093
P2860
P304
P356
10.1172/JCI109521
P407
P577
1979-09-01T00:00:00Z