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Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in miceCharacterization of an almost full-length cDNA coding for human blood coagulation factor XThe nucleotide sequence of the gene for human protein CThe structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAsThermodynamic linkage between the S1 site, the Na+ site, and the Ca2+ site in the protease domain of human activated protein C (APC). Sodium ion in the APC crystal structure is coordinated to four carbonyl groups from two separate loopsThe 2.8 A crystal structure of Gla-domainless activated protein CActivated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction.Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1.Activated protein C action in inflammationThe protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implicationsModeling zymogen protein C.Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells.Hereditary thrombophilia: identification of nonsense and missense mutations in the protein C geneEvolution and organization of the human protein C gene.The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin.Cloning and characterization of two cDNAs coding for human von Willebrand factor.EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.Antibody-probed conformational transitions in the protease domain of human factor IX upon calcium binding and zymogen activation: putative high-affinity Ca(2+)-binding site in the protease domainTherapeutic levels of human protein C in rats after retroviral vector-mediated hepatic gene therapy.The protein C pathway and pathologic processesMolecular basis of gamma-carboxylation. Role of the propeptide in the vitamin K-dependent proteins.A novel protein C-factor VII chimera provides new insights into the structural requirements for cytoprotective PAR1 signaling.Direct detection of point mutations by mismatch analysis: application to haemophilia B.Impaired secretion of the elongated mutant of protein C (protein C-Nagoya). Molecular and cellular basis for hereditary protein C deficiency.Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain.Recombinant human protein C derivatives: altered response to calcium resulting in enhanced activation by thrombinCharacterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones.Multifunctional specificity of the protein C/activated protein C Gla domain.Successful treatment of homozygous protein C deficiency by hepatic transplantationGene analysis of heterozygous protein C deficiency in a patient with pulmonary arterial thromboembolism.Rapid detection of a protein C gene mutation present in the asymptomatic and not in the thrombosis-prone lineage.Activated factor VII: my story.A comparative study of partial primary structures of the catalytic region of mammalian protein C.Gly74Ser mutation in protein C causes thrombosis due to a defect in protein S-dependent anticoagulant function.
P2860
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P2860
description
1984 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1984
@ast
im August 1984 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1984/08/01)
@sk
vědecký článek publikovaný v roce 1984
@cs
wetenschappelijk artikel (gepubliceerd op 1984/08/01)
@nl
наукова стаття, опублікована в серпні 1984
@uk
name
Characterization of a cDNA coding for human protein C
@ast
Characterization of a cDNA coding for human protein C
@en
Characterization of a cDNA coding for human protein C
@nl
type
label
Characterization of a cDNA coding for human protein C
@ast
Characterization of a cDNA coding for human protein C
@en
Characterization of a cDNA coding for human protein C
@nl
prefLabel
Characterization of a cDNA coding for human protein C
@ast
Characterization of a cDNA coding for human protein C
@en
Characterization of a cDNA coding for human protein C
@nl
P2860
P356
P1476
Characterization of a cDNA coding for human protein C
@en
P2093
E. W. Davie
P2860
P304
P356
10.1073/PNAS.81.15.4766
P407
P577
1984-08-01T00:00:00Z