MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
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The crucial impact of lysosomes in aging and longevityCapitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseasesCell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription FactorsAutophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegansThe Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signalsA lysosome-centered view of nutrient homeostasisTFEB at a glanceGuidelines for monitoring autophagy in Caenorhabditis elegansTranscriptional and epigenetic regulation of autophagy in agingEssential role for autophagy in life span extensionAn Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host DefenseRegulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stressHigh- and low-throughput scoring of fat mass and body fat distribution in C. elegans.Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.Lysosomal adaptation: how the lysosome responds to external cuesNovel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisDifferential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegansInnate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genesmTOR and lysosome regulation.Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeCaenorhabditis elegans metabolic gene regulatory networks govern the cellular economy.Signals from the lysosome: a control centre for cellular clearance and energy metabolism.Genome-wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans developmentThe paradox of mitochondrial dysfunction and extended longevity.Lysosome: regulator of lipid degradation pathways.Lipid droplet protein LID-1 mediates ATGL-1-dependent lipolysis during fasting in Caenorhabditis elegans.Autophagy and human disease: emerging themes.AMPK at the nexus of energetics and aging.Ethanol-induced differential gene expression and acetyl-CoA metabolism in a longevity model of the nematode Caenorhabditis elegans.Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signalingLongevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegansEctopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7.The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debrisRegulation of Liver Metabolism by Autophagy.Regulation of body fat in Caenorhabditis elegans.Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signalsDrosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway.
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MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 21 April 2013
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
@en
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
@nl
type
label
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
@en
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
@nl
prefLabel
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
@en
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
@nl
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P356
P1433
P1476
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
@en
P2093
Eyleen J O'Rourke
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P2888
P304
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10.1038/NCB2741
P50
P577
2013-04-21T00:00:00Z