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Incorporating genetics and genomics in risk assessment for inhaled manganese: from data to policyPARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's diseaseMitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cellsParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disordersFour decades of neurodegenerative disease research: how far we have come!VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's DiseaseATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neuronsPTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolismSTEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's diseaseParkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factorsParkinsonism in patients with a history of amphetamine exposure.Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.High expression levels of the D686N Parkinson's disease mutation in VPS35 induces α-synuclein-dependent toxicity in yeastPros and cons of a prion-like pathogenesis in Parkinson's diseaseCarbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson's diseaseEnvironmental tobacco smoke and Parkinson's disease.Risk for Parkinson's disease among patients with osteoarthritis: a Danish cohort study.Gender differences in the IL6 -174G>C and ESR2 1730G>A polymorphisms and the risk of Parkinson's disease.Cognitive impairment and dementia in Parkinson's disease: clinical features, diagnosis, and management.Clinical approach to Parkinson's disease: features, diagnosis, and principles of management.VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function.Redefining Parkinson's disease research using induced pluripotent stem cellsA PTEN translational isoform has PTEN-like activity.PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation.Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells.Proteomic profiling of phosphoproteins and glycoproteins responsive to wild-type alpha-synuclein accumulation and aggregation.Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles.Emerging pathways in genetic Parkinson's disease: tangles, Lewy bodies and LRRK2.What causes cell death in Parkinson's disease?Transcranial brain sonography findings in Parkinson's disease: implications for pathogenesis, early diagnosis and therapy.Molecular pathogenesis of Parkinson disease: insights from genetic studies.Ageing, neurodegeneration and Parkinson's disease.Mitochondrial proteomics as a selective tool for unraveling Parkinson's disease pathogenesis.Peripheral biomarkers of Parkinson's disease as early reporters of central neurodegeneration.Cellular repair strategies in Parkinson's disease.The neuropathology of genetic Parkinson's disease.Regulation of Parkin E3 ubiquitin ligase activity.Rodent models and contemporary molecular techniques: notable feats yet incomplete explanations of Parkinson's disease pathogenesis.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Update on the genetics of Parkinson's disease.
@en
Update on the genetics of Parkinson's disease.
@nl
type
label
Update on the genetics of Parkinson's disease.
@en
Update on the genetics of Parkinson's disease.
@nl
prefLabel
Update on the genetics of Parkinson's disease.
@en
Update on the genetics of Parkinson's disease.
@nl
P2860
P356
P1433
P1476
Update on the genetics of Parkinson's disease.
@en
P2860
P304
P356
10.1002/MDS.21676
P407
P478
22 Suppl 17
P577
2007-09-01T00:00:00Z