Deletion of Cx43 from osteocytes results in defective bone material properties but does not decrease extrinsic strength in cortical bone
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The osteocyte as a therapeutic target in the treatment of osteoporosisConnexin 43 hemichannels and intracellular signaling in bone cellsA novel autosomal recessive GJA1 missense mutation linked to Craniometaphyseal dysplasiaUp-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis in Gja1Jrt/+ stromal cell cultures.Connexins and pannexins in the skeleton: gap junctions, hemichannels and moreDefective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.Connexins in the skeletonRemoving or truncating connexin 43 in murine osteocytes alters cortical geometry, nanoscale morphology, and tissue mechanics in the tibia.Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness.Osteocytic connexin 43 is not required for the increase in bone mass induced by intermittent PTH administration in male mice.High bone mass in mice lacking Cx37 because of defective osteoclast differentiation.An intact connexin43 is required to enhance signaling and gene expression in osteoblast-like cells.Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.The "connexin" between bone cells and skeletal functions.Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-κB Ligand and Tumor Necrosis Factor Alpha SecretionConnexin43 and the Intercellular Signaling Network Regulating Skeletal Remodeling.Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation.Brucella and Osteoarticular Cell Activation: Partners in Crime.Lactation-Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue.Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss.Ibandronate increases sclerostin levels and bone strength in male patients with idiopathic osteoporosis.Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.Reversal of loss of bone mass in old mice treated with mefloquine
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P2860
Deletion of Cx43 from osteocytes results in defective bone material properties but does not decrease extrinsic strength in cortical bone
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 August 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Deletion of Cx43 from osteocyt ...... nsic strength in cortical bone
@en
Deletion of Cx43 from osteocyt ...... sic strength in cortical bone.
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type
label
Deletion of Cx43 from osteocyt ...... nsic strength in cortical bone
@en
Deletion of Cx43 from osteocyt ...... sic strength in cortical bone.
@nl
prefLabel
Deletion of Cx43 from osteocyt ...... nsic strength in cortical bone
@en
Deletion of Cx43 from osteocyt ...... sic strength in cortical bone.
@nl
P2093
P2860
P1476
Deletion of Cx43 from osteocyt ...... nsic strength in cortical bone
@en
P2093
Jiliang Li
Lilian I Plotkin
Lisa M Miller
Mark T Nelson
Meghan E Faillace
Nicoletta Bivi
P2860
P2888
P304
P356
10.1007/S00223-012-9628-Z
P407
P577
2012-08-04T00:00:00Z