Targeted oncogene activation by site-specific recombination in transgenic mice
about
Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defenseIdentification of promoter regions in the human genome by using a retroviral plasmid library-based functional reporter gene assayInactivation of Icmt inhibits transformation by oncogenic K-Ras and B-RafA mouse model for Costello syndrome reveals an Ang II-mediated hypertensive conditionMN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in miceEfficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectorsPhage integrases for the construction and manipulation of transgenic mammalsGenetic alteration and gene expression modulation during cancer progressionConditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.Strict control of telomerase activation using Cre-mediated inversion.EndothelinFrom Gene Targeting to Genome Editing: Transgenic animals applications and beyondGene targeting in mice: a reviewStrategies to achieve conditional gene mutation in miceAmygdala NRG1-ErbB4 is critical for the modulation of anxiety-like behaviors.A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in miceModelling T-cell memory by genetic marking of memory T cells in vivoFLPe functions in zebrafish embryosMolecular neuroanatomy's "Three Gs": a primerThe sld genetic defect: two intronic CA repeats promote insertion of the subsequent intron and mRNA decayMyocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in miceThe in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathyHaploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephalyMice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birthThe leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney developmentSelective expression of presenilin 1 in neural progenitor cells rescues the cerebral hemorrhages and cortical lamination defects in presenilin 1-null mutant miceDeletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor developmentSalt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2SSTR5 ablation in islet results in alterations in glucose homeostasis in miceMacrophage Wnt7b is critical for kidney repair and regenerationA modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promotersRapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassetteEfficient in vivo manipulation of mouse genomic sequences at the zygote stageA cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cellsProtamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cellsExpression of a gonadotropin-releasing hormone receptor-simian virus 40 T-antigen transgene has sex-specific effects on the reproductive axis.Directed evolution of the site specificity of Cre recombinase.Short and long-term effects of hVEGF-A(165) in Cre-activated transgenic mice.A randomized library approach to identifying functional lox site domains for the Cre recombinase.Split-CreERT2: temporal control of DNA recombination mediated by split-Cre protein fragment complementation.
P2860
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P2860
Targeted oncogene activation by site-specific recombination in transgenic mice
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Targeted oncogene activation by site-specific recombination in transgenic mice
@ast
Targeted oncogene activation by site-specific recombination in transgenic mice
@en
Targeted oncogene activation by site-specific recombination in transgenic mice
@nl
type
label
Targeted oncogene activation by site-specific recombination in transgenic mice
@ast
Targeted oncogene activation by site-specific recombination in transgenic mice
@en
Targeted oncogene activation by site-specific recombination in transgenic mice
@nl
prefLabel
Targeted oncogene activation by site-specific recombination in transgenic mice
@ast
Targeted oncogene activation by site-specific recombination in transgenic mice
@en
Targeted oncogene activation by site-specific recombination in transgenic mice
@nl
P2093
P2860
P3181
P356
P1476
Targeted oncogene activation by site-specific recombination in transgenic mice
@en
P2093
B Mosinger
H Westphal
K L Mulder
R W Manning
P2860
P304
P3181
P356
10.1073/PNAS.89.14.6232
P407
P577
1992-07-15T00:00:00Z