DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. - Wikidata - awgldk - TriplyDB

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.

http://www.wikidata.org/entity/Q37061484

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PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication Role of DNA polymerase κ in the maintenance of genomic stability Microsatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomes Master molecule, heal thyself.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Rad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation.Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.Cell-free Xenopus egg extracts for studying DNA damage response pathways.Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells.Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells.Regulation of DNA Replication in Early Embryonic Cleavages.Molecular mechanisms of DNA replication checkpoint activation The identification of translesion DNA synthesis regulators: Inhibitors in the spotlight.PrimPol-A new polymerase on the block.Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses.A role for DNA polymerase θ in the timing of DNA replication.Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts.Human Translesion Polymerase κ Exhibits Enhanced Activity and Reduced Fidelity Two Nucleotides from G-Quadruplex DNA.Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas.Six Germline Genetic Variations Impair the Translesion Synthesis Activity of Human DNA Polymerase κ.Pol κ in replication checkpoint.Around and beyond 53BP1 Nuclear Bodies.N2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ.Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe.Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo.Association of POLK polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients.

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DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.

http://www.wikidata.org/entity/Q37061484

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 25 June 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@en

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@nl

type

label

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@en

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@nl

prefLabel

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@en

DNA polymerase κ-dependent DNA ...... important for CHK1 activation.

@nl

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The EMBO Journal

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DNA polymerase κ-dependent DNA ...... important for CHK1 activation

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Bénédicte Recolin

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Caixia Guo

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Christophe Cazaux

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Emma Ohl-Séguy

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Errol Friedberg

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Jean-Sébastien Hoffmann

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Laura Pierini

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Marie-Jeanne Pillaire

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Naoko Niimi

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Petr Grúz

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P2860

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

Replication protein A-mediated recruitment and activation of Rad17 complexes

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

The DNA Damage Response: Making It Safe to Play with Knives

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2172-2185

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scholarly article

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10.1038/EMBOJ.2013.148

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15

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32

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Domenico Maiorano

Siem Van Der Laan

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2013-06-25T00:00:00Z

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242015388

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23799366

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