Ets2-dependent stromal regulation of mouse mammary tumors
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Novel role for PDEF in epithelial cell migration and invasionNew highlights on stroma-epithelial interactions in breast cancer.Molecular mechanisms of ETS transcription factor-mediated tumorigenesisEts2 in tumor fibroblasts promotes angiogenesis in breast cancerRegulation of the transcription factor Ets-1 by DNA-mediated homo-dimerizationIncreased Skin Tumor Incidence and Keratinocyte Hyper-Proliferation in a Mouse Model of Down SyndromeAltered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryosAn ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasisControl of mammary tumor differentiation by SKI-606 (bosutinib).The ETS family of oncogenic transcription factors in solid tumours.Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.A compendium of the mouse mammary tumor biologist: from the initial observations in the house mouse to the development of genetically engineered mice.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis.Role of infiltrated leucocytes in tumour growth and spread.The use of mouse models for understanding the biology of down syndrome and agingEts2 regulates colonic stem cells and sensitivity to tumorigenesis.Prostate-derived Ets transcription factor overexpression is associated with nodal metastasis and hormone receptor positivity in invasive breast cancerEts2 is required for trophoblast stem cell self-renewal.Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stromaEts transcription factors in intestinal morphogenesis, homeostasis and disease.Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes.Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment.Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.Eureka! Ets a target for fibrosis!Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter.The role of ets factors in tumor angiogenesis.Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors.The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice.Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.
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P2860
Ets2-dependent stromal regulation of mouse mammary tumors
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2003
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ets2-dependent stromal regulation of mouse mammary tumors
@en
Ets2-dependent stromal regulation of mouse mammary tumors.
@nl
type
label
Ets2-dependent stromal regulation of mouse mammary tumors
@en
Ets2-dependent stromal regulation of mouse mammary tumors.
@nl
prefLabel
Ets2-dependent stromal regulation of mouse mammary tumors
@en
Ets2-dependent stromal regulation of mouse mammary tumors.
@nl
P2093
P2860
P1476
Ets2-dependent stromal regulation of mouse mammary tumors
@en
P2093
Albert K Man
Craig A Hauser
Jacqueline Lesperance
John A Tynan
Lawrence J T Young
Robert D Cardiff
Robert G Oshima
William J Muller
P2860
P304
P356
10.1128/MCB.23.23.8614-8625.2003
P407
P577
2003-12-01T00:00:00Z