Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea
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The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKsInfection Strategies of Intestinal Parasite Pathogens and Host Cell ResponsesDextran sodium sulphate colitis mouse model: traps and tricksMechanisms Underlying Dysregulation of Electrolyte Absorption in Inflammatory Bowel Disease-Associated DiarrheaReduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrheaReduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine ColitisEnhanced K(+) secretion in dextran sulfate-induced colitis reflects upregulation of large conductance apical K(+) channels (BK; Kcnma1)Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colonDownregulation of the NHE3-binding PDZ-adaptor protein PDZK1 expression during cytokine-induced inflammation in interleukin-10-deficient mice.Transport via the transcytotic pathway makes prostasin available as a substrate for matriptaseNHE3 modulates the severity of colitis in IL-10-deficient miceEvidence for a causal link between adaptor protein PDZK1 downregulation and Na⁺/H⁺ exchanger NHE3 dysfunction in human and murine colitisIon transport in the intestine.Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis.Transcriptional regulation of the intestinal luminal Na⁺ and Cl⁻ transporters.Na-H Exchanger Isoform-2 (NHE2) Mediates Butyrate-dependent Na+ Absorption in Dextran Sulfate Sodium (DSS)-induced ColitisHuman rotavirus strain Wa downregulates NHE1 and NHE6 expressions in rotavirus-infected Caco-2 cells.Mechanism of down regulation of Na-H exchanger-2 in experimental colitis.Secretory diarrhoea: mechanisms and emerging therapies.SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangersKeratin 8 knockdown leads to loss of the chloride transporter DRA in the colonCongenital secretory diarrhoea caused by activating germline mutations in GUCY2C.Reduced colonic microbial diversity is associated with colitis in NHE3-deficient miceMechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3NHE3 regulatory complexesPathophysiology of Intestinal Na+/H+ exchange.Intestinal inflammation and the enterocyte transportome.Impeded protein folding and function in active inflammatory bowel disease.Deciphering the mechanisms of the Na+/H+ exchanger-3 regulation in organ dysfunction.The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis.Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter.Traditional and emerging roles for the SLC9 Na+/H+ exchangers.Epithelial transport in inflammatory bowel diseases.Altered cGMP dynamics at the plasma membrane contribute to diarrhea in ulcerative colitis.Role of epithelial ion transports in inflammatory bowel disease.Plasticity of the brush border - the yin and yang of intestinal homeostasis.Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward Clostridium difficile Toxins TcdA and TcdB.Somatostatin regulates NHE8 protein expression via the ERK1/2 MAPK pathway in DSS-induced colitis mice.Tumor necrosis factor-α represses the expression of NHE2 through NF-κB activation in intestinal epithelial cell model, C2BBe1.HIV Exposure to the Epithelia in Ectocervical and Colon Tissues Induces Inflammatory Cytokines Without Tight Junction Disruption.
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Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Downregulation of sodium trans ...... ors to IBD-associated diarrhea
@en
Downregulation of sodium trans ...... rs to IBD-associated diarrhea.
@nl
type
label
Downregulation of sodium trans ...... ors to IBD-associated diarrhea
@en
Downregulation of sodium trans ...... rs to IBD-associated diarrhea.
@nl
prefLabel
Downregulation of sodium trans ...... ors to IBD-associated diarrhea
@en
Downregulation of sodium trans ...... rs to IBD-associated diarrhea.
@nl
P2093
P2860
P356
P1476
Downregulation of sodium trans ...... ors to IBD-associated diarrhea
@en
P2093
Carmen Cuffari
Laurie Conklin
Lisa Wu Datta
Mark Donowitz
Mary L Harris
Nicholas C Zachos
Philip Alex
Sean Sullivan
Steven R Brant
Themos Dassopoulos
P2860
P304
P356
10.1002/IBD.20743
P577
2009-02-01T00:00:00Z