Glycoengineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation.
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Structural Basis and Catalytic Mechanism for the Dual Functional Endo-β-N-Acetylglucosaminidase AImmune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesEndo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1-->4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylationA combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylationAnalysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2007-2008.The Amazing Transglycosylation Activity of Endo-β-N-acetylglucosaminidasesIntramolecular N-glycan/polypeptide interactions observed at multiple N-glycan remodeling steps through [(13)C,(15)N]-N-acetylglucosamine labeling of immunoglobulin G1.Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure-activity relationships for amylin receptor agonism.Convergent synthesis of homogeneous Glc1Man9GlcNAc2-protein and derivatives as ligands of molecular chaperones in protein quality control.Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.Emerging technologies for making glycan-defined glycoproteinsGlycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptidesA two-step enzymatic glycosylation of polypeptides with complex N-glycansChemoenzymatic Glyco-engineering of Monoclonal Antibodies.Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein.Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycansEnzymatic transglycosylation for glycoconjugate synthesis.Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.Toward automated oligosaccharide synthesis.Synthesis of post-translationally modified proteins.Glycosylation: impact, control and improvement during therapeutic protein production.Chemoenzymatic Synthesis and Receptor Binding of Mannose-6-Phosphate (M6P)-Containing Glycoprotein Ligands Reveal Unusual Structural Requirements for M6P Receptor Recognition.Convergent chemo-enzymatic synthesis of mannosylated glycopeptides; targeting of putative vaccine candidates to antigen presenting cells.Chemoenzymatic Fc glycosylation via engineered aldehyde tags.Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.The ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling.Evaluation of a glycoengineered monoclonal antibody via LC-MS analysis in combination with multiple enzymatic digestion.Glycosylation of pramlintide: synthetic glycopeptides that display in vitro and in vivo activities as amylin receptor agonists.Chemoenzymatic synthesis of the immunoglobulin domain of Tim-3 carrying a complex-type N-glycan by using a one-pot ligation.Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands.Chemoenzymatic Glycan Remodeling of Natural and Recombinant Glycoproteins.Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies.
P2860
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P2860
Glycoengineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@en
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@nl
type
label
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@en
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@nl
prefLabel
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@en
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@nl
P2093
P2860
P356
P1433
P1476
Glycoengineering of human IgG1 ...... chemoenzymatic glycosylation.
@en
P2093
P2860
P304
10294-10304
P356
10.1021/BI800874Y
P407
P577
2008-09-05T00:00:00Z