CXCR4 mediates the proliferation of glioblastoma progenitor cells.
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Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsGlioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and RadioresistanceG protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenuesChemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic AgentsCancer stem cells in basic science and in translational oncology: can we translate into clinical application?CXCR4 expression in prostate cancer progenitor cellsComparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targetsCXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomasCXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis.Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells.Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling.AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments.Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.Glioma Stemlike Cells Enhance the Killing of Glioma Differentiated Cells by Cytotoxic Lymphocytes.CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosisInhibition of stromal CXCR4 impairs development of lung metastases.Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair.Cryptotanshinone targets tumor-initiating cells through down-regulation of stemness genes expression.Brain tumor stem cell multipotency correlates with nanog expression and extent of passaging in human glioblastoma xenografts.Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma.Tumor initiating cells in malignant gliomas: biology and implications for therapy.Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats.Analysis of Chemopredictive Assay for Targeting Cancer Stem Cells in Glioblastoma Patients.CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target.Characteristic features of stem cells in glioblastomas: from cellular biology to genetics.The role of the CXCR4 cell surface chemokine receptor in glioma biology.Systematic review of protein biomarkers of invasive behavior in glioblastoma.The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets.Role of Forkhead Box Class O proteins in cancer progression and metastasis.CXCR4 expression varies significantly among different subtypes of glioblastoma multiforme (GBM) and its low expression or hypermethylation might predict favorable overall survival.ER-mitochondria contacts control surface glycan expression and sensitivity to killer lymphocytes in glioma stem-like cells.Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile.CXCR7 and CXCR4 Expressions in Infiltrative Astrocytomas and Their Interactions with HIF1α Expression and IDH1 Mutation.CXCL12 secreted from glioma stem cells regulates their proliferation.CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.Isolation, cultivation and characterization of CD133+ stem cells from human glioblastoma.CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties.
P2860
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P2860
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@en
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@nl
type
label
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@en
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@nl
prefLabel
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@en
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@nl
P2093
P2860
P1433
P1476
CXCR4 mediates the proliferation of glioblastoma progenitor cells.
@en
P2093
Charles B Stevenson
Khubaib Y Mapara
Moneeb Ehtesham
Reid C Thompson
P2860
P304
P356
10.1016/J.CANLET.2008.09.034
P407
P577
2008-11-12T00:00:00Z