Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile. - Wikidata - awgldk - TriplyDB

Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile.

Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile.

http://www.wikidata.org/entity/Q38790973

about

Paradoxical role of SOX2 in gastric cancer Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Role of SOX family of transcription factors in central nervous system tumors Brain tumor stem cells: Molecular characteristics and their impact on therapy Targeting SOX2 as a Therapeutic Strategy in Glioblastoma The expression of SALL4 in patients with gliomas: high level of SALL4 expression is correlated with poor outcome YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation Glioblastoma development in mouse brain: general reduction of OCTs and mislocalization of OCT3 transporter and subsequent uptake of ASP(+) substrate to the nuclei Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+)The differentiation of pancreatic tumor-initiating cells by vitronectin can be blocked by cilengitide Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma.SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells The multiple roles for Sox2 in stem cell maintenance and tumorigenesis.LIN28 is involved in glioma carcinogenesis and predicts outcomes of glioblastoma multiforme patients.Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency.PDGF and PDGF receptors in glioma.Platelet-derived growth factor in glioblastoma-driver or biomarker?Expression of SOX2 in oral squamous cell carcinoma and the association with lymph node metastasis The dark side of SOX2: cancer - a comprehensive overview.Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.Rapamycin inhibited the function of lung CSCs via SOX2.Sox2: regulation of expression and contribution to brain tumors.FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells.Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation.G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells The quest for self-identity: not all cancer stem cells are the same.SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesis.Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.Overexpression of Golgi phosphoprotein-3 (GOLPH3) in glioblastoma multiforme is associated with worse prognosis.The Influence of EGFR Inactivation on the Radiation Response in High Grade Glioma.Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis

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P2860

Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile.

http://www.wikidata.org/entity/Q38790973

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Identification of a SOX2-depen ...... inhibitor sensitivity profile.

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Identification of a SOX2-depen ...... inhibitor sensitivity profile.

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Identification of a SOX2-depen ...... inhibitor sensitivity profile.

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Identification of a SOX2-depen ...... inhibitor sensitivity profile.

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Arne Ostman

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Göran Hesselager

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Monica Nistér

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Saskia Hoefs

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Xiaobing He

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P2860

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

An integrated genomic analysis of human glioblastoma multiforme

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model

Prospective identification of tumorigenic breast cancer cells

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Identification and expansion of human colon-cancer-initiating cells

Identification of human brain tumour initiating cells

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1178-1191

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10.1093/NEUONC/NOR113

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11

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Maja Bradic Lindh

Daniel Hägerstrand

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2011-09-22T00:00:00Z

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3199157

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