The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes - Wikidata - awgldk - TriplyDB

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

http://www.wikidata.org/entity/Q37072688

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Insulin receptor signaling in normal and insulin-resistant states The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases Mammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway ENPP1 affects insulin action and secretion: evidences from in vitro studies.The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.GRB10 gene and type 2 diabetes in Whites.Drosophila tribbles antagonizes insulin signaling-mediated growth and metabolism via interactions with Akt kinase Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women Silence of TRIB3 suppresses atherosclerosis and stabilizes plaques in diabetic ApoE-/-/LDL receptor-/- mice.Role of TRIB3 in diabetic and overnutrition-induced atherosclerosis.Whole genome association scan for genetic polymorphisms influencing information processing speed Variants of insulin-signaling inhibitor genes in type 2 diabetes and related metabolic abnormalities.Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes.TRIB3 functional Q84R polymorphism is a risk factor for metabolic syndrome and carotid atherosclerosis.Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties Tribbles: 'puzzling' regulators of cell signalling.From genotype to human β cell phenotype and beyond.Replication of genome-wide association signals in Asian Indians with early-onset type 2 diabetes.IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes.Gene polymorphisms of adiponectin and leptin receptor are associated with early onset of type 2 diabetes mellitus in the Taiwanese population.Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity.Tribbles 3: A potential player in diabetic aortic remodelling.

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The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

http://www.wikidata.org/entity/Q37072688

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

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2008年學術文章

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2008年學術文章

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name

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

@en

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.

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type

label

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

@en

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.

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prefLabel

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

@en

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.

@nl

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The Journal of Clinical Endocrinology and Metabolism

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The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

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Christine Powers

http://www.w3.org/2001/XMLSchema#string

Daniela Scarpelli

http://www.w3.org/2001/XMLSchema#string

Eleonora Morini

http://www.w3.org/2001/XMLSchema#string

Francesco Perticone

http://www.w3.org/2001/XMLSchema#string

Manisha Chandalia

http://www.w3.org/2001/XMLSchema#string

Nicola Abate

http://www.w3.org/2001/XMLSchema#string

Rong Li

http://www.w3.org/2001/XMLSchema#string

Yuan-Yuan Zhang

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P2860

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

ENPP1 gene, insulin resistance and related clinical outcomes

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

Discerning the ancestry of European Americans in genetic association studies

Analysis and application of European genetic substructure using 300 K SNP information.

Type 2 diabetes in the young: the evolving epidemic.

Genetics of type 2 diabetes mellitus: status and perspectives.

From mice to men: insights into the insulin resistance syndromes.

Genome-wide association studies provide new insights into type 2 diabetes aetiology.

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190-196

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scholarly article

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10.1210/JC.2008-1365

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1

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94

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Bruno Dallapiccola

Silvia Del Guerra

Piero Marchetti

Sabrina Prudente

Francesco Andreozzi

Alessandro Doria

Vincenzo Trischitta

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2008-11-04T00:00:00Z

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18984671

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type-2 diabetes

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2630876

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