KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis
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Leukocyte Ig-Like Receptors - A Model for MHC Class I Disease AssociationsHLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic RatsTwo new cases of KIR3DP1, KIR2DL4-negative genotypes, one of which is also lacking KIR3DL2.The danger model approach to the pathogenesis of the rheumatic diseases.The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains.Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo.Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue.Ankylosing spondylitis: from cells to genesThe arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review).KIR and HLA under pressure: evidences of coevolution across worldwide populations.Innate Immune Activation Can Trigger Experimental Spondyloarthritis in HLA-B27/Huβ2m Transgenic Rats.α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells.The Activating Human NK Cell Receptor KIR2DS2 Recognizes a β2-Microglobulin-Independent Ligand on Cancer Cells.The D0 Ig-like domain plays a central role in the stronger binding of KIR3DL2 to B27 free H chain dimers.Functional Genomics and Its Bench-to-Bedside Translation Pertaining to the Identified Susceptibility Alleles and Loci in Ankylosing Spondylitis.Causes and consequences of endoplasmic reticulum stress in rheumatic disease.Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.Targeted Delivery of the HLA-B∗27-Binding Peptide into the Endoplasmic Reticulum Suppresses the IL-23/IL-17 Axis of Immune Cells in Spondylarthritis.
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P2860
KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 25 February 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
KIR3DL2 binds to HLA-B27 dimer ...... ells in ankylosing spondylitis
@en
KIR3DL2 binds to HLA-B27 dimer ...... lls in ankylosing spondylitis.
@nl
type
label
KIR3DL2 binds to HLA-B27 dimer ...... ells in ankylosing spondylitis
@en
KIR3DL2 binds to HLA-B27 dimer ...... lls in ankylosing spondylitis.
@nl
prefLabel
KIR3DL2 binds to HLA-B27 dimer ...... ells in ankylosing spondylitis
@en
KIR3DL2 binds to HLA-B27 dimer ...... lls in ankylosing spondylitis.
@nl
P2093
P2860
P356
P1476
KIR3DL2 binds to HLA-B27 dimer ...... ells in ankylosing spondylitis
@en
P2093
Anna Ridley
Anthoni Chan
Christopher Piper
Hiroko Hatano
Isabel Wong-Baeza
Jackie Shaw
Kirsty McHugh
Oliwia Rysnik
Simon Brackenbridge
Simon Kollnberger
P2860
P304
P356
10.4049/JIMMUNOL.1202926
P407
P577
2013-02-25T00:00:00Z