Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat
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Regulators and Effectors of Arf GTPases in NeutrophilsCOPI budding within the Golgi stackThe exomer cargo adaptor structure reveals a novel GTPase-binding domainA Structure-Based Mechanism for Arf1-Dependent Recruitment of Coatomer to MembranesArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions.Three homologous ArfGAPs participate in coat protein I-mediated transport.Arf GAPs: gatekeepers of vesicle generation.Models for the functions of Arf GAPs.Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling.A stretch of polybasic residues mediates Cdc42 GTPase-activating protein (CdGAP) binding to phosphatidylinositol 3,4,5-trisphosphate and regulates its GAP activity.GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.The ArfGAP2/3 Glo3 and ergosterol collaborate in transport of a subset of cargoes.Arf GAP2 is positively regulated by coatomer and cargo.Mechanisms of COPI vesicle formation.Bidirectional transport between the trans-Golgi network and the endosomal system.Physical aspects of COPI vesicle formation.A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment.The ArfGAP protein MoGlo3 regulates the development and pathogenicity of Magnaporthe oryzae.9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.GAPs in the context of COPI: Enzymes, coat components or both?Conserved molecular mechanisms underlying homeostasis of the Golgi complex.Recruitment of Arf1-GDP to Golgi by Glo3p-type ArfGAPs is crucial for golgi maintenance and plant growth.ARFGAP; cargo; v-SNAREs and p24 proteins bind nascent COPI complexARFGAP; cargo; vSNARES and p24 proteins bind COPI vesicles at GolgiDistinct role of subcomplexes of the COPI coat in the regulation of ArfGAP2 activity.A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking
P2860
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P2860
Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Discrete determinants in ArfGA ...... nd regulation by the COPI coat
@en
Discrete determinants in ArfGA ...... d regulation by the COPI coat.
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type
label
Discrete determinants in ArfGA ...... nd regulation by the COPI coat
@en
Discrete determinants in ArfGA ...... d regulation by the COPI coat.
@nl
prefLabel
Discrete determinants in ArfGA ...... nd regulation by the COPI coat
@en
Discrete determinants in ArfGA ...... d regulation by the COPI coat.
@nl
P2093
P2860
P356
P1476
Discrete determinants in ArfGA ...... nd regulation by the COPI coat
@en
P2093
Anna Parnis
Dan Cassel
Joëlle Bigay
Lena Kliouchnikov
Moran Rawet
Noga Goldfeder
P2860
P304
P356
10.1091/MBC.E08-10-1010
P577
2008-12-24T00:00:00Z