Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP
about
The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusionsPhosphorylation site dynamics of early T-cell receptor signalingβ1 integrins regulate fibroblast chemotaxis through control of N-WASP stability.Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acidA nucleator arms race: cellular control of actin assemblyAllosteric N-WASP activation by an inter-SH3 domain linker in NckSrc kinases regulate de novo actin polymerization during exocytosis in neuroendocrine chromaffin cells.Cortactin, an actin binding protein, regulates GLUT4 translocation via actin filament remodelingPhysical mechanisms of signal integration by WASP family proteins.Syk regulates multiple signaling pathways leading to CX3CL1 chemotaxis in macrophages.Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization.Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamicsBruton's tyrosine kinase regulates Shigella flexneri dissemination in HT-29 intestinal cellsSmall molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.X-linked thrombocytopenia causing mutations in WASP (L46P and A47D) impair T cell chemotaxis.Binding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile α motif (SAM) domains.Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp.A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection.Bacterial subversion of host actin dynamics at the plasma membrane.Regulation of cytoskeletal dynamics at the immune synapse: new stars join the actin troupeRequirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophagesRNA therapeutics targeting osteoclast-mediated excessive bone resorption.Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein Kinase C.The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites.Signaling during pathogen infection.The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation.Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coatRole of protein-tyrosine phosphatases in regulation of osteoclastic activity.The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationRegulation of WASp by phosphorylation: Activation or other functions?Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis.Actin cytoskeleton remodelling by sex steroids in neurones.Wiskott-Aldrich syndrome protein--dynamic regulation of actin homeostasis: from activation through function and signal termination in T lymphocytes.Multiscale modeling of cell shape from the actin cytoskeleton.Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome.Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophagesTyrosine kinases, drugs, and Shigella flexneri dissemination.
P2860
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P2860
Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@ast
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en-gb
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@nl
type
label
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@ast
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en-gb
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@nl
prefLabel
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@ast
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en-gb
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@nl
P2860
P356
P1476
Protein-tyrosine kinase and GT ...... e protein (WASP)/neuronal WASP
@en
P2093
Eduardo Torres
Michael K Rosen
P2860
P304
P356
10.1074/JBC.M509416200
P407
P577
2006-02-10T00:00:00Z