Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation
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Parkin Regulation and Neurodegenerative DisordersParkin structure and functionPrimary skin fibroblasts as a model of Parkinson's diseaseThe Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons.ERK/MAPK regulates ERRĪ³ expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer.LRRK2 function on actin and microtubule dynamics in Parkinson diseaseMicrotubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts.Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis.Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases.Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegansCytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.Parkin mutations reduce the complexity of neuronal processes in iPSC-derived human neuronsDifferential programming of p53-deficient embryonic cells during rotenone block.Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells.Manganese-induced toxicity in normal and human B lymphocyte cell lines containing a homozygous mutation in parkin.Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic modelsParkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release.Back to the tubule: microtubule dynamics in Parkinson's disease.Live cell imaging of cytoskeletal dynamics in neurons using fluorescence photoactivation.Parkin, A Top Level Manager in the Cell's Sanitation Department.The interplay of neuronal mitochondrial dynamics and bioenergetics: implications for Parkinson's diseaseAn emerging role of PARK2 in cancer.Agmatine Protects Against 6-OHDA-Induced Apoptosis, and ERK and Akt/GSK Disruption in SH-SY5Y Cells.Microtubule Destabilization Paves the Way to Parkinson's Disease.Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection.The protease Omi cleaves the mitogen-activated protein kinase kinase MEK1 to inhibit microglial activation.Shedding of phosphatidylserine from developing erythroid cells involves microtubule depolymerization and affects membrane lipid composition.Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.Cytoskeletal changes in diseases of the nervous system
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Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation
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article cientĆfic
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article scientifique
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articolo scientifico
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artigo cientĆfico
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bilimsel makale
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scientific article published on 11 December 2008
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vedeckĆ½ ÄlĆ”nok
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vetenskaplig artikel
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Parkin protects dopaminergic n ...... ated protein kinase activation
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Parkin protects dopaminergic n ...... ted protein kinase activation.
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type
label
Parkin protects dopaminergic n ...... ated protein kinase activation
@en
Parkin protects dopaminergic n ...... ted protein kinase activation.
@nl
prefLabel
Parkin protects dopaminergic n ...... ated protein kinase activation
@en
Parkin protects dopaminergic n ...... ted protein kinase activation.
@nl
P2093
P2860
P356
P1476
Parkin protects dopaminergic n ...... ated protein kinase activation
@en
P2093
Houbo Jiang
Kazuhiro Nakaso
P2860
P304
P356
10.1074/JBC.M806245200
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P577
2008-12-11T00:00:00Z