Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
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The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directionsShigella Diversity and Changing Landscape: Insights for the Twenty-First CenturyTherapeutic Potential to Modify the Mucus Barrier in Inflammatory Bowel DiseaseBreaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disordersMucosal healing and deep remission: what does it mean?A refined palate: bacterial consumption of host glycans in the gutKeeping bugs in check: The mucus layer as a critical component in maintaining intestinal homeostasisIntestinal permeability--a new target for disease prevention and therapyCD103+ CD11b+ Dendritic Cells Induce Th17 T Cells in Muc2-Deficient Mice with Extensively Spread ColitisAGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucusSpontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitisDissecting the Interplay Between Intestinal Microbiota and Host Immunity in Health and Disease: Lessons Learned from Germfree and Gnotobiotic Animal ModelsMechanisms Underlying Dysregulation of Electrolyte Absorption in Inflammatory Bowel Disease-Associated DiarrheaReduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine ColitisDeep transcriptional sequencing of mucosal challenge compartment from rhesus macaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activationPostnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection.Oxidative stress-induced mitochondrial dysfunction in a normal colon epithelial cell lineInteraction of microbes with mucus and mucins: recent developmentsMicrobiota-induced peritrophic matrix regulates midgut homeostasis and prevents systemic infection of malaria vector mosquitoes.Exploring the influence of the gut microbiota and probiotics on health: a symposium report.Microbiota activation and regulation of innate and adaptive immunity.Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein.Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus.Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer.The gastrointestinal mucus system in health and diseaseRole of Janus kinase 3 in mucosal differentiation and predisposition to colitisMucus and the goblet cell.B cells as a critical node in the microbiota-host immune system network.Starving our microbial self: the deleterious consequences of a diet deficient in microbiota-accessible carbohydratesIntestinal inflammation and mucosal barrier function.Microbiota organization is a distinct feature of proximal colorectal cancersThe mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.Probiotics can generate FoxP3 T-cell responses in the small intestine and simultaneously inducing CD4 and CD8 T cell activation in the large intestine.Adenomatous polyps are driven by microbe-instigated focal inflammation and are controlled by IL-10-producing T cells.Innate and adaptive immunity interact to quench microbiome flagellar motility in the gutThe composition of the gut microbiota throughout life, with an emphasis on early life.The composition of the gut microbiota shapes the colon mucus barrier.Gut ecosystem: how microbes help us.Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- mice.Influences of the colonic microbiome on the mucous gel layer in ulcerative colitis
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Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 20 February 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Bacteria penetrate the normall ...... tients with ulcerative colitis
@en
Bacteria penetrate the normall ...... ients with ulcerative colitis.
@nl
type
label
Bacteria penetrate the normall ...... tients with ulcerative colitis
@en
Bacteria penetrate the normall ...... ients with ulcerative colitis.
@nl
prefLabel
Bacteria penetrate the normall ...... tients with ulcerative colitis
@en
Bacteria penetrate the normall ...... ients with ulcerative colitis.
@nl
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P2860
P50
P1433
P1476
Bacteria penetrate the normall ...... tients with ulcerative colitis
@en
P2093
Andrew T Gewirtz
Fayez K Ghishan
Frederic A Carvalho
Henrik Sjövall
Jenny K Gustafsson
Jessica Holmén-Larsson
P2860
P304
P356
10.1136/GUTJNL-2012-303207
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P577
2013-02-20T00:00:00Z