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New Perspectives on DNA and RNA Triplexes As Effectors of Biological ActivityMethods to detect replication-dependent and replication-independent DNA structure-induced genetic instabilityHuman DHX9 helicase unwinds triple-helical DNA structuresDHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cellsTTS mapping: integrative WEB tool for analysis of triplex formation target DNA sequences, G-quadruplets and non-protein coding regulatory DNA elements in the human genomeHuman cancers express mutator phenotypes: origin, consequences and targeting.Expressed Structurally-stable Inverted Duplicates in Mammalian Genomes as Functional Noncoding ElementsAlternative DNA structure formation in the mutagenic human c-MYC promoter.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisNon-B DNA structure-induced genetic instability and evolution.Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells.A distinct triplex DNA unwinding activity of ChlR1 helicaseOn the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Sensitive and label-free biosensing of RNA with predicted secondary structures by a triplex affinity capture methodp53 Specifically Binds Triplex DNA In Vitro and in CellsThe cellular etiology of chromosome translocations.Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequencesPotential in vivo roles of nucleic acid triple-helices.DNA methylation in cancer development, diagnosis and therapy--multiple opportunities for genotoxic agents to act as methylome disruptors or remediators.Stress-induced modulators of repeat instability and genome evolutionThe yin and yang of repair mechanisms in DNA structure-induced genetic instability.Mechanisms of oncogenic chromosomal translocations.Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instabilityReproducibility of SNV-calling in multiple sequencing runs from single tumors.Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases.Replication stalling and DNA microsatellite instability.Effects of Replication and Transcription on DNA Structure-Related Genetic InstabilityRegulation of DNA Replication through Natural Impediments in the Eukaryotic Genome.Break-induced replication links microsatellite expansion to complex genome rearrangements.Detection of cis- and trans-acting Factors in DNA Structure-Induced Genetic Instability Using In silico and Cellular ApproachesPathways for double-strand break repair in genetically unstable Z-DNA-forming sequences.PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCERTriplex-induced DNA damage response.Molecular topography of the MED12-deleted region in smooth muscle tumors: a possible link between non-B DNA structures and hypermutability.Z-DNA stabilization is dominated by the Hofmeister effect.A 'DNA replication' signature of progression and negative outcome in colorectal cancer.Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.DNA as a one-dimensional chiral material. II. Dynamics of the structural transition between B form and Z form.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
DNA structure-induced genomic instability in vivo.
@en
DNA structure-induced genomic instability in vivo.
@nl
type
label
DNA structure-induced genomic instability in vivo.
@en
DNA structure-induced genomic instability in vivo.
@nl
prefLabel
DNA structure-induced genomic instability in vivo.
@en
DNA structure-induced genomic instability in vivo.
@nl
P2093
P2860
P356
P1476
DNA structure-induced genomic instability in vivo.
@en
P2093
Guliang Wang
John DiGiovanni
Karen M Vasquez
Steve Carbajal
P2860
P304
P356
10.1093/JNCI/DJN385
P407
P577
2008-12-09T00:00:00Z