The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate.
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Sigma receptor ligand, (+)-pentazocine, suppresses inflammatory responses of retinal microgliaDiabetes Accelerates Retinal Neuronal Cell Death In A Mouse Model of Endogenous Hyperhomocysteinemia.σ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cellsSigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons.Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand.An update on the development of drugs for neuropsychiatric disorders: focusing on the sigma 1 receptor ligand.Novel drugs and their targets in the potential treatment of diabetic retinopathy.Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptorIntravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors.Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells.The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cellsLate-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).Sensitivity of staurosporine-induced differentiated RGC-5 cells to homocysteineDiabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1(+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent MechanismThe genetic mechanisms of primary angle closure glaucoma.In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine.Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2Akita/+ Murine Model of Diabetic RetinopathyA prototypical Sigma-1 receptor antagonist protects against brain ischemia.Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine RetinaExpression, subcellular localization, and regulation of sigma receptor in retinal muller cells.Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration.Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.The pharmacology of sigma-1 receptors.Changes in iron-regulatory proteins in the aged rodent neural retina.Sigma receptor 1 modulates ER stress and Bcl2 in murine retina.Sigma-1 Receptors and Neurodegenerative Diseases: Towards a Hypothesis of Sigma-1 Receptors as Amplifiers of Neurodegeneration and Neuroprotection.The Role of Sigma1R in Mammalian Retina.Peeking into Sigma-1 Receptor Functions Through the Retina.Haloperidol Affects Plasticity of Differentiated NG-108 Cells Through σ1R/IP3R1 Complex.Retinal ganglion cell loss in diabetes associated with elevated homocysteine.Protective effects of the sigma agonist Pre-084 in the rat retina.Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes.The Role of Sigma 1 Receptor as a Neuroprotective Target in Glaucoma.An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration.Sigma Receptor 1 Is Preferentially Involved in Modulation of N-Methyl- D -Aspartate Receptor-Mediated Light-Evoked Excitatory Postsynaptic Currents in Rat Retinal Ganglion Cells
P2860
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P2860
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The sigma receptor ligand (+)- ...... by homocysteine and glutamate.
@en
The sigma receptor ligand
@nl
type
label
The sigma receptor ligand (+)- ...... by homocysteine and glutamate.
@en
The sigma receptor ligand
@nl
prefLabel
The sigma receptor ligand (+)- ...... by homocysteine and glutamate.
@en
The sigma receptor ligand
@nl
P2093
P2860
P1476
The sigma receptor ligand (+)- ...... by homocysteine and glutamate.
@en
P2093
Mohammad S Ola
Neeraj Agarwal
Pamela Moore Martin
Sylvia B Smith
P2860
P356
10.1016/J.MOLBRAINRES.2003.12.019
P577
2004-04-01T00:00:00Z