Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. - Wikidata - awgldk - TriplyDB

Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours.

Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours.

http://www.wikidata.org/entity/Q37099095

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FES kinases are required for oncogenic FLT3 signaling Clinicopathological significance of c-KIT mutation in gastrointestinal stromal tumors: a systematic review and meta-analysis Myxoid epithelioid gastrointestinal stromal tumor harboring an unreported PDGFRA mutation: report of a case and review of the literature Clinical practice guidelines for patients with gastrointestinal stromal tumor in Taiwan Mechanisms of drug resistance in kinases.Efficacy of Imatinib in Patients with Platelet-Derived Growth Factor Receptor Alpha-Mutated Gastrointestinal Stromal Tumors.P53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in GISTs. An immunohistochemical study of 104 cases.Phase II study of dovitinib in patients with metastatic and/or unresectable gastrointestinal stromal tumours after failure of imatinib and sunitinib.Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors.qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.Molecular basis and management of gastrointestinal stromal tumors MiRNA profiling of gastrointestinal stromal tumors by next-generation sequencing NCCN Task Force report: update on the management of patients with gastrointestinal stromal tumors.Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)Downsizing treatment with tyrosine kinase inhibitors in patients with advanced gastrointestinal stromal tumors improved resectability.Perspective on updated treatment guidelines for patients with gastrointestinal stromal tumors.Is there something other than imatinib mesilate in therapeutic options for GIST?All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein.Genetic aberrations of gastrointestinal stromal tumors.The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting.Histopathology of gastrointestinal stromal tumor.A gist of gastrointestinal stromal tumors: A review.Analysis of prognostic factors impacting oncologic outcomes after neoadjuvant tyrosine kinase inhibitor therapy for gastrointestinal stromal tumors.GEIS 2013 guidelines for gastrointestinal sarcomas (GIST)Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation.Gastrointestinal stromal tumor - an evolving concept.MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.Beyond H&E: integration of nucleic acid-based analyses into diagnostic pathology.A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT).Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age Approval summary: imatinib mesylate in the adjuvant treatment of malignant gastrointestinal stromal tumors.Carney triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondria Gastric schwannoma: a clinicopathologic study of 51 cases and critical review of the literature Gastrointestinal tumors of the colon and rectum Presence of PDGFRA and DOG1 mutations in gastrointestinal stromal tumors among Chinese population.Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial.Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or PDGFRA mutations.

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Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours.

http://www.wikidata.org/entity/Q37099095

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article científic

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artigo científico

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bilimsel makale

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scientific article published on 28 February 2008

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vedecký článok

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vetenskaplig artikel

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Clinical significance of oncog ...... trointestinal stromal tumours.

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Clinical significance of oncog ...... trointestinal stromal tumours.

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Clinical significance of oncog ...... trointestinal stromal tumours.

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Clinical significance of oncog ...... trointestinal stromal tumours.

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Clinical significance of oncog ...... trointestinal stromal tumours.

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Clinical significance of oncog ...... trointestinal stromal tumours.

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J.1365-2559.2008.02977.X

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Clinical significance of oncog ...... trointestinal stromal tumours.

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J Lasota

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M Miettinen

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P2860

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size.

The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors

Activating c-kit gene mutations in human germ cell tumors

KIT mutations are common in testicular seminomas.

Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases

Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas.

KIT gene deletions at the intron 10-exon 11 boundary in GI stromal tumors

Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors.

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.

Germline-activating mutation in the kinase domain of KIT gene in familial gastrointestinal stromal tumors

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10.1111/J.1365-2559.2008.02977.X

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