The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo. - Wikidata - awgldk - TriplyDB

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

http://www.wikidata.org/entity/Q37099920

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Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining.Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.DNA Ligase IV regulates XRCC4 nuclear localization.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation.

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P2860

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

http://www.wikidata.org/entity/Q37099920

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 December 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@en

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@nl

type

label

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@en

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@nl

prefLabel

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@en

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@nl

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Molecular and Cellular Biology

P1476

The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.

@en

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Isabelle Callebaut

http://www.w3.org/2001/XMLSchema#string

Jean-Paul Mornon

http://www.w3.org/2001/XMLSchema#string

Jean-Pierre de Villartay

http://www.w3.org/2001/XMLSchema#string

Laurent Malivert

http://www.w3.org/2001/XMLSchema#string

Paola Rivera-Munoz

http://www.w3.org/2001/XMLSchema#string

Patrick Revy

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P2860

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination

Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

Crystal structure of human XLF: a twist in nonhomologous DNA end-joining

NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway.

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1116-1122

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scholarly article

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10.1128/MCB.01521-08

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5

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29

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Jean-Pierre de Villartay

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2008-12-22T00:00:00Z

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23685361

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19103754

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2643816

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