Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease.
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Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseReduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's diseaseMulticenter analysis of glucocerebrosidase mutations in Parkinson's disease.Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivationThe p.L302P mutation in the lysosomal enzyme gene SMPD1 is a risk factor for Parkinson diseaseLipid pathway alterations in Parkinson's disease primary visual cortexThe incidence of Parkinsonism in patients with type 1 Gaucher disease: data from the ICGG Gaucher RegistryMinimal peroxide exposure of neuronal cells induces multifaceted adaptive responsesIdentifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach.Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.Patch clamp-assisted single neuron lipidomics.Gaucher disease: insights from a rare Mendelian disorder.The link between the GBA gene and parkinsonismMutations in the ATP13A2 gene and Parkinsonism: a preliminary review.The pallidopyramidal syndromes: nosology, aetiology and pathogenesis.Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study.Novel histopathologic findings in molecularly-confirmed pantothenate kinase-associated neurodegenerationAlpha-synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseasesIdentification of a set of endogenous reference genes for miRNA expression studies in Parkinson's disease blood samplesProgressive decline of glucocerebrosidase in aging and Parkinson's disease.Mutation of the parkinsonism gene ATP13A2 causes neuronal ceroid-lipofuscinosisClinical approach to Parkinson's disease: features, diagnosis, and principles of management.Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons.The role of glucocerebrosidase mutations in Parkinson disease and Lewy body disordersMembrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories.Pantothenate kinase-associated neurodegeneration is not a synucleinopathyThe association between mutations in the lysosomal protein glucocerebrosidase and parkinsonismGenetic determinants of circulating sphingolipid concentrations in European populations.Lysosomal impairment in Parkinson's disease.A plural role for lipids in motor neuron diseases: energy, signaling and structure.Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond.Syndromes of neurodegeneration with brain iron accumulation (NBIA): an update on clinical presentations, histological and genetic underpinnings, and treatment considerations.Glucocerebrosidase involvement in Parkinson disease and other synucleinopathies.Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemia.Glucocerebrosidase mutations and the pathogenesis of Parkinson disease.Genetics and genomics of Parkinson's disease.Defective lipid metabolism in neurodegeneration with brain iron accumulation (NBIA) syndromes: not only a matter of iron.
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Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@en
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@nl
type
label
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@en
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@nl
prefLabel
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@en
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@nl
P2860
P50
P1433
P1476
Emerging pathways in genetic P ...... tabolism in Lewy body disease.
@en
P2093
P2860
P304
P356
10.1111/J.1742-4658.2008.06709.X
P407
P577
2008-12-01T00:00:00Z