Omega-O-acylceramide, a lipid essential for mammalian survival.
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Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humansLipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain lengthFatty acid transporters in skin development, function and diseaseStructural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorumThe importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrierTwo modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cyclePotential Applications of Phyto-Derived Ceramides in Improving Epidermal Barrier Function.Retinal very long-chain PUFAs: new insights from studies on ELOVL4 proteinRetinal sphingolipids and their very-long-chain fatty acid-containing species.Effects of in utero exposure of C57BL/6J mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin on epidermal permeability barrier development and functionRole of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophiesEssential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation.Genetics and molecular pathology of Stargardt-like macular degeneration.Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.The role of fatty acid elongation in epidermal structure and function.The expression and regulation of enzymes mediating the biosynthesis of triglycerides and phospholipids in keratinocytes/epidermisThe role of fatty aldehyde dehydrogenase in epidermal structure and function.EGFR regulation of epidermal barrier function.Cellular changes that accompany shedding of human corneocytes.2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.Disruption of the Sjögren-Larsson Syndrome Gene Aldh3a2 in Mice Increases Keratinocyte Growth and Retards Skin Barrier RecoverySphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasisImpaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid productionThe Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: IMPLICATION OF AN EPOXIDE HYDROLASE IN THE TRANSFORMATIONS OF LINOLEATE.Genetics and prospective therapeutic targets for Sjögren-Larsson Syndrome.pH-regulated mechanisms account for pigment-type differences in epidermal barrier function1-O-acylceramides are natural components of human and mouse epidermisAltered sphingoid base profiles predict compromised membrane structure and permeability in atopic dermatitisEndogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.Ceramide signaling in mammalian epidermis.Glycosphingolipids--nature, function, and pharmacological modulation.PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.Fatty aldehyde and fatty alcohol metabolism: review and importance for epidermal structure and function.In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4.Role of fatty acid transporters in epidermis: Implications for health and diseaseFat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.The stratum corneum: the rampart of the mammalian body.
P2860
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P2860
Omega-O-acylceramide, a lipid essential for mammalian survival.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 10 March 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Omega-O-acylceramide, a lipid essential for mammalian survival.
@en
Omega-O-acylceramide, a lipid essential for mammalian survival.
@nl
type
label
Omega-O-acylceramide, a lipid essential for mammalian survival.
@en
Omega-O-acylceramide, a lipid essential for mammalian survival.
@nl
prefLabel
Omega-O-acylceramide, a lipid essential for mammalian survival.
@en
Omega-O-acylceramide, a lipid essential for mammalian survival.
@nl
P1476
Omega-O-acylceramide, a lipid essential for mammalian survival.
@en
P2093
Walter M Holleran
Yoshikazu Uchida
P356
10.1016/J.JDERMSCI.2008.01.002
P577
2008-03-10T00:00:00Z